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Table 6 Closed-Loop Fluid Management - Uncertain PPV Conditions

From: Evaluation of a novel closed-loop fluid-administration system based on dynamic predictors of fluid responsiveness: an in silico simulation study

 

Perfect PPV

Biased PPV

Fluctuating PPV

Biased & Fluctuating PPV

First Bolus (min)

52.6 ± 0.9

53.4 ± 1.4

51.9 ± 4

52.6 ± 3.9

Total Fluid Given (ml)

2476 ± 85

2466 ± 80

2428 ± 159

2435 ± 131

Mean Arterial Pressure (mmHg)

82.1 ± 0.7

82.1 ± 0.6

82 ± 1.2

82 ± 1.6

Mean Cardiac Output (L/min)

6.3 ± 0.1

6.3 ± 0.1

6.2 ± 0.2

6.2 ± 0.2

Minimum Cardiac Output (L/min)

5.8 ± 0.2

5.9 ± 0.2

5.7 ± 0.3

5.6 ± 0.4

Final Cardiac Output (L/min)

6.4 ± 0.1

6.4 ± 0.1

6.4 ± 0.1

6.3 ± 0.2

Cardiac Output During Case, Coefficient of Variance (%)

5.4 ± 1.3

5.4 ± 1.1

6.4 ± 2.0

7.0 ± 3.2

  1. n = 20 each group. Data are reported as mean +/- standard deviation. p > 0.05 for all comparisons. PPV: pulse pressure variation.