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Table 6 Closed-Loop Fluid Management - Uncertain PPV Conditions

From: Evaluation of a novel closed-loop fluid-administration system based on dynamic predictors of fluid responsiveness: an in silico simulation study

  Perfect PPV Biased PPV Fluctuating PPV Biased & Fluctuating PPV
First Bolus (min) 52.6 ± 0.9 53.4 ± 1.4 51.9 ± 4 52.6 ± 3.9
Total Fluid Given (ml) 2476 ± 85 2466 ± 80 2428 ± 159 2435 ± 131
Mean Arterial Pressure (mmHg) 82.1 ± 0.7 82.1 ± 0.6 82 ± 1.2 82 ± 1.6
Mean Cardiac Output (L/min) 6.3 ± 0.1 6.3 ± 0.1 6.2 ± 0.2 6.2 ± 0.2
Minimum Cardiac Output (L/min) 5.8 ± 0.2 5.9 ± 0.2 5.7 ± 0.3 5.6 ± 0.4
Final Cardiac Output (L/min) 6.4 ± 0.1 6.4 ± 0.1 6.4 ± 0.1 6.3 ± 0.2
Cardiac Output During Case, Coefficient of Variance (%) 5.4 ± 1.3 5.4 ± 1.1 6.4 ± 2.0 7.0 ± 3.2
  1. n = 20 each group. Data are reported as mean +/- standard deviation. p > 0.05 for all comparisons. PPV: pulse pressure variation.