Table 2 Randomized controlled trials of shorter versus longer antibiotic therapy that included patients with bacteremia.
From: Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis
Author | Syndrome | All patients blood cultured? | Short-arm group, number (percentage) bacteremic | Long-arm group, number (percentage) bacteremic |
|---|---|---|---|---|
Chowdhary et al. [26] | Non-Staphylococcus aureus bacteremia | Yes | 26/26 (100%) | 26/26 (100%) |
| Â | S. aureus bacteremia | Yes | 7/7 (100%) | 7/7 (100%) |
Runyon et al. [28] | Peritonitis | Yes | 9/43 (20.9%) | 17/47 (36.2%) |
Chaudhry et al. [29] | Peritonitis | Yes | 6/25 (24%) | 8/25 (32%) |
Jernelius et al. [47] | Pyelonephritis | Yes | 5/32 (15.6%) | 4/29 (13.8%) |
Cheng et al. [48] | Pyelonephritis | Yes | 1/41 (2.4%) | 3/39 (7.7%) |
Engle et al. [30] | Pneumonia | Yes | 0/14 (0%) | 0/12 (0%) |
Engle et al. [31] | Pneumonia | Yes | 0/35 (0%) | 0/38 (0%) |
Vuori-Holopainen et al. [32] | Pneumonia | Yes | N/A | N/A |
Tellier et al. [36] | Pneumonia | Yes | 14/187 (7.5%) | 9/191 (4.7%) |
File et al. [35] | Pneumonia | Yes | N/A | N/A |
Dunbar et al. [37] | Pneumonia | Yes | 7/256 (2.7%) | 7/272 (2.6%) |
Leophonte et al. [39] | Pneumonia | Yes | 11/125 (8.8%) | 12/119 (10.1%) |
Siegel et al. [38] | Pneumonia | Yes | 2/24 (8.3%) | 4/22 (18.2%) |
El Moussaoui et al. [40] | Pneumonia | Unclear | 6/56 (10.7%) | 8/63 (12.7%) |
Chastre et al. [42] | Pneumonia | Yes | 14/197 (7.1%) | 14/204 (6.9%) |