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Table 4 Logistic regression analysis of 28-day mortality

From: IL17A genetic variation is associated with altered susceptibility to Gram-positive infection and mortality of severe sepsis

 

SPH

 

VASST

 
 

Odds Ratio (95% CI)

P

Odds Ratio (95% CI)

P

Age-yearsr

1.029 (1.016-1.042)

1.4 × 10-5

1.021 (1.008-1.034)

0.0011

Female

0.99 (0.66-1.49)

0.99

0.92 (0.62-1.35)

0.67

Surgical

0.70 (0.45-1.07)

0.10

0.84 (0.53-1.33)

0.46

IL17A rs1974226 G allele

1.44 (1.04-2.02)

0.029

1.67 (1.17-2.40)

0.0052

  1. SPH, St. Paul's Hospital; VASST, Vasopressin and Septic Shock Trial.
  2. Odds ratio was calculated for patients with septic shock using a logistic regression including potential cofounding factors: age, gender (female versus male), surgical versus medical primary diagnosis, and IL17A rs1974226 G allele (GG versus GA versus AA) as covariates.