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Figure 1 | Critical Care

Figure 1

From: IL17A genetic variation is associated with altered susceptibility to Gram-positive infection and mortality of severe sepsis

Figure 1

Frequency of patients who had Gram-positive or Gram-negative bacterial culture-positive by IL17A rs1974226 genotype in two cohorts of severe sepsis. IL17A rs1974226 GG genotype patients had an increased culture-positive rate of Gram-positive bacteria compared to the AA/AG genotype patients and a decreased rate of Gram-negative bacteria in two cohorts (AA/AG versus GG, SPH, Gram-positive P = 0.0036, Gram-negative P = 0.0086; VASST, Gram-positive P = 0.011, Gram-negative P = 0.13). SPH, St Paul's Hospital; VASST, Vasopressin and Septic Shock Trial. P values were calculated using chi-square test. *P < 0.05

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