CPR | Control | P value | ||||
---|---|---|---|---|---|---|
n = 36 | n = 20 | |||||
% | % | |||||
Age (years) | 63.9 ± 2.1 | 65.7 ± 2.5 | 0.58/ns | |||
Gender | Male | 28 | 78 | 16 | 80 | 0.85/ns |
Female | 8 | 22 | 4 | 20 | ||
Cause of CA or | Cardiac | 23 | 64 | 20 | 100 | <0.005 |
hospital admission | Non-cardiac | 10 | 28 | 0 | 0 | |
Unknown | 3 | 8 | 0 | 0 | ||
Coronary angiography | 23 | 64 | 12 | 60 | 0.78/ns | |
Location of CPR | out-of-hospital | 27 | 75 | |||
in-hospital | 9 | 25 | ||||
Duration of CPR (min) | 21.8 ± 2.5 | |||||
No-flow time (min) | 4.5 ± 0.8 | |||||
Initial rhythm | VT/VF | 20 | 56 | |||
Asystole/PEA | 16 | 44 | ||||
Outcome | Survival to discharge | 14 | 39 | 20 | 100 | |
GOS (survivors) at discharge | 4.4 ± 0.2 | 5.0 ± 0.0 | ||||
SOFA score day 1 | 11.0 ± 0.4 | |||||
SOFA score day 2 | 10.6 ± 0.4 | |||||
Medication at ICU | Vasopressors | 20 | 56 | 0 | 0 | <0.001 |
Thrombolysis | 3 | 8 | 0 | 0 | 0.18/ns | |
GPIIb/IIIa blockers | 16 | 44 | 2 | 10 | < 0.001 | |
Acetylsalicylic acid | 25 | 69 | 15 | 75 | 0.66/ns | |
Clopidogrel | 21 | 58 | 12 | 60 | 0.90/ns | |
Medication prior to event | Statins | 8 | 22 | 12 | 60 | <0.01 |
Consecutive organ | Acute renal failure | 8 | 22 | 0 | 0 | <0.05 |
failure | Acute liver failure | 3 | 8 | 0 | 0 | 0.54/ns |
Acute heart failure | 4 | 11 | 0 | 0 | 0.29/ns | |
Co-morbidities | CAD | 24 | 67 | 14 | 70 | 0.80/ns |
PAD | 4 | 11 | 5 | 25 | 0.26/ns | |
Chronic heart failure | 2 | 6 | 3 | 15 | 0.34/ns | |
Chronic renal insufficiency | 4 | 11 | 2 | 10 | 0.99/ns | |
Liver insufficiency | 4 | 11 | 0 | 0 | 0.29/ns | |
Pulmonary disease | 9 | 25 | 6 | 30 | 0.69/ns | |
Cardiovascular risk | Hypertension | 16 | 44 | 15 | 75 | <0.05 |
factors | Hyperlipidemia | 6 | 17 | 11 | 55 | <0.005 |
Diabetes | 9 | 25 | 2 | 10 | 0.29/ns | |
Smoking | 7 | 19 | 8 | 40 | 0.10/ns | |
Laboratory values | Leukocytes/μL (day 1) | 15.5 ± 1.1 | 7.7 ± 0.5 | <0.001 | ||
Leukocytes/μL (day 2) | 13.7 ± 1.5 | 7.7 ± 1.0 | <0.005 | |||
Platelets/μL (day 1) | 203.7 ± 12.3 | 231.9 ± 12.9 | 0.12/ns | |||
Platelets/μL (day 2) | 183.9 ± 12.4 | 200.9 ± 41.0 | 0.7/ns | |||
CRP mg/L (day 1) | 37.2 ± 11.3 | 8.7 ± 2.9 | <0.05 | |||
CRP mg/L (day 2) | 56.8 ± 12.1 | 6.3 ± 1.4 | <0.001 |