Table 1 Physiology response to spontaneous breathing (SB Group) and control ventilation (CV group).
| Â | Time = 0 h | Time = 8 h | ||||
|---|---|---|---|---|---|---|
| Â | CV group ( n = 8) | SB group ( n = 8) | P 1 | CV group ( n = 8) | SB group ( n = 8) | P 2 |
HR (breaths/minute) | 232.2 ± 23.7 | 239.3 ± 28.2 | 0.66 | 219.3 ± 19.8 | 235.2 ± 21.7 | 0.22 |
MBP (mmHg) | 89.0 ± 11.0 | 91.4 ± 16.5 | 0.75 | 92.6 ± 17.8 | 90.7 ± 9.4 | 0.81 |
CVP (mmHg) | 3.6 ± 0.7 | 3.7 ± 0.7 | 0.74 | 3.6 ± 0.5 | 3.9 ± 0.6 | 0.41 |
VT (ml/kg) | 12.9 ± 0.8 | 12.3 ± 1.7 | 0.54 | 12.2 ± 1.4 | 13 ± 0.6 | 0.24 |
VTspont (ml/kg) | 0 | 0 | - | 0 | 10.9 ± 0.8 | - |
RRTOT (breaths/minute) | 38.3 ± 4.1 | 37.5 ± 2.7 | 0.69 | 45.0 ± 4.5 | 39.5 ± 7.4 | 0.15 |
RRspont (breaths/minute) | 0 | 0 | - | 0 | 8.8 ± 5.4 | - |
MVTOT (L/minute) | 1.26 ± 0.28 | 1.04 ± 0.23 | 0.18 | 1.50 ± 0.26 | 1.18 ± 0.33 | 0.10 |
PI (cmH2O) | 8 ± 1.6 | 8 ± 1.5 | 1.00 | 9 ± 0.6 | 8.3 ± 1.8 | 0.43 |
Pmean (cmH2O) | 4.67 ± 0.8 | 4.67 ± 0.5 | 1.00 | 5.33 ± 0.8 | 5.00 ± 0.6 | 0.45 |
Compliance(ml/cmH2O) | 5.4 ± 0.7 | 5.55 ± 2.6 | 0.87 | 4.3 ± 0.8 | 7.6 ± 2.4* | 0.01 |
Arterial pH | 7.34 ± 0.08 | 7.38 ± 0.06 | 0.27 | 7.24 ± 0.05* | 7.33 ± 0.08 | 0.04 |
PaCO2 (mmHg) | 48.5 ± 8.7 | 43.9 ± 6.2 | 0.32 | 51.5 ± 7.8 | 38.2 ± 7.1* | 0.01 |
PaO2/FiO2 (mmHg) | 399.0 ± 46.4 | 430.3 ± 40.0 | 0.24 | 437.7 ± 60.3 | 476.3 ± 11.6 | 0.40 |
Lactic acid (mmol/L) | 1.0 ± 0.2 | 1.4 ± 0.4 | 0.10 | 2.1 ± 0.4 | 1.7 ± 0.7 | 0.70 |