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Table 4 Near-infrared spectroscopy and sidestream dark field variables

From: Effects of changes in arterial pressure on organ perfusion during septic shock

 

65 mm Hg

75 mm Hg

85 mm Hg

65 mm Hg

NIRS variables

    

   StO2 baseline, percentage

82.5 (79.0-85.9)

81.0 (77.0-85.0)

81.2 (77.6-84.7)

77.8 (73.6-82.1)

   Descending slope, percentage/minute

−14.8 (−18.0 - −11.6)

−14.5 (−18.9 - −10.0)

−16.4 (−22.0 - −10.9)

−15.7 (−21.9 - −9.4)

   nirVO2I, arbitrary units

139 (114-165)

122 (98-146)

153 (109-196)

129 (93-165)

   Delta StO2, percentage

7.4 (5.3-9.5)

8.4 (5.2-11.6)

7.7 (5.4-9.9)

7.4 (5-9.7)

   AUC ratio, percentage

0.11 (0.05-0.16)

0.12 (0.09-0.15)

0.10 (0.08-0.14)

0.10 (0.07-0.15)

   Ascending slope, percentage/minute

111 (80-141)

172 (115-228)a

177 (122-232)a

114 (94-134)

SDF variables

    

   Total vessel density

12.8 (10.5-15.0)

13.2 (11.1-15.3)

14.3 (12.9-15.7)

13.7 (11.0-16.4)

   Small vessel density

10.7 (8.5-12.9)

11 (8.5-13.4)

11.6 (10.1-13.1)

11.7 (9.0-14.3)

   PVD, vessels/mm

11.0 (8.6-13.3)

12.0 (9.4-14.5)

13.2 (11.9-14.5)a

12.1 (9.2-14.9)

   Small PVD, vessels/mm

9.1 (6.4-11.9)

9.8 (6.9-12.8)

10.7 (9.0-12.3)

10.3 (7.1-13.5)

   All PPV, percentage

85.9 (80.1-91.6)

89.5 (83.7-95.2)

92.6 (89.9-95.3)

87.7 (79.9-95.6)

   Large PPV, percentage

95.5 (93.6-97.4)

95.4 (88.8-102.0)

97.5 (95.2-99.7)

89.8 (82.7-96.9)

   Small PPV, percentage

83.6 (76.1-91.0)

87.9 (81.8-94.0)

91.1 (87.9-94.3)

86.4 (76.3-96.5)

   Microvascular flow index

2.4 (2.2-2.7)

2.7 (2.4-2.9)

2.9 (2.8-2.9)a

2.5 (2.2-2.9)

  1. aP <0.05 versus baseline. AUC, area under the curve; NIRS, near-infrared spectroscopy; nirVO2I, reverse descending slope multiplied by the average tissue hemoglobin index during the first occlusion minute; PPV, proportion of perfused vessels; PVD, perfused vessel density; SDF, sidestream dark field; StO2, thenar muscle oxygen saturation.