Table 3 Subject characteristics in shock meeting physiological criteria for transfusion
From: Red blood cell transfusion and outcomes in patients with acute lung injury, sepsis and shock
Characteristics | Transfused (n= 20) | Not transfused (n= 65) | P value |
|---|---|---|---|
Age, years | 65 (15) | 51 (14) | < 0.01 |
Male | 13 (65) | 25 (38) | 0.04 |
Race | Â | Â | Â |
   White | 14 (70) | 45 (69) | 0.49 |
   Black | 5 (25) | 11 (17) |  |
   Other | 1 (5) | 9 (14) |  |
Chronic comorbidities | Â | Â | Â |
Diabetes | 5 (26) | 14 (22) | 0.71 |
Hepatic failure | 1 (5) | 0 (0) | 0.07 |
Alcohol use | 0 (0) | 9 (14) | 0.09 |
Prior myocardial infarction | 0 (0) | 3 (5) | 0.39 |
Congestive heart failure | 0 (0) | 5 (8) | 0.26 |
Admission type | Â | Â | Â |
   Medical | 16 (80) | 61 (94) | 0.08 |
   Surgical | 4 (20) | 4 (6) |  |
   Other | 0 (0) | 0 (0) |  |
Randomization arm | Â | Â | Â |
   Liberal fluid (vs. conservative) | 11 (55) | 29 (45) | 0.42 |
   Pulmonary artery (vs. central venous) catheter | 14 (70) | 46 (71) | 0.95 |
   APACHE III score | 122 (7) | 103 (3) | 0.02 |
   Days from ALI diagnosis to randomization | 1 (0 to 1) | 1 (0 to 1) | 0.96 |
   Days from hospital admission to randomization | 2 (1 to 11) | 2 (1 to 4) | 0.49 |
   Days from ICU admission to randomization | 1 (0.5 to 1.5) | 1 (1 to 2) | 0.20 |
   PaO2/FiO2 ratio at randomization | 107 (60 to 144) | 89 (66 to 152) | 0.85 |
Physiological parameters during exposure window | Â | Â | Â |
   Hemoglobin nadir, g/dL | 8.2 (1.2) | 9.0 (0.8) | 0.02 |
   cVO2/mVO2 ratio nadir | 59 (1) | 59 (10) | 0.99 |
   MAP nadir | 62 (7) | 62 (9) | 0.80 |
   Mean MAP | 72 (8) | 73 (7) | 0.70 |
   Multiple pressors | 12 (60) | 32 (49) | 0.45 |
   Total fluid received, L | 5.4 (3.0) | 5.0 (2.9) | 0.54 |