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Table 1 Severe inflammatory response syndrome is diagnosed if two or more of these criteria are fulfilled

From: Bench-to-beside review: Acute-on-chronic liver failure - linking the gut, liver and systemic circulation

Body temperature of greater than 38.5°C or less than 35°C

Heart rate of greater than 90 beats per minute

Respiratory rate of greater than 20 breaths per minute or arterial partial pressure of carbon dioxide (PaCO2) of less than 32 mm Hg

White blood cell count of greater than 12,000 cells/mm3 or less than 4,000 cells/mm3 or greater than 10% immature forms