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Table 1 Clinical characteristics of 135 HIV-infected patients who were admitted to the ICUs at the National Taiwan University Hospital from 2001 to 2010

From: Admissions to intensive care unit of HIV-infected patients in the era of highly active antiretroviral therapy: etiology and prognostic factors

Characteristics

135 patients

Median age (years)

39 (31-50)

Male sex

123 (91.1)

Race/ethnicity

 

   Taiwanese

133 (98.5)

   other Asians

2 (1.5)

HIV risk factor

 

   Homosexual

53 (39.3)

   Bisexual

7 (5.2)

   Injecting drug use

16 (11.9)

   Transfusion-related

3 (2.2)

   Heterosexual/other/unknown

56 (41.5)

HIV-related characteristics

 

   Newly diagnosed HIV infection

60 (44.4)

   Time since HIV diagnosis (month)

1.23 (0-36)

   Time since AIDS diagnosis (month)

0.73 (0-26)

   Prior HAART at hospital admission

49 (36.3)

   Duration of HAART for patients on prior HAART (month)a

13 (6-48)

   HAART initiated during ICU stay

12 (8.9)

   HAART use in ICU

82 (60.7)

   HIV viral load (copies/ml)b

217,000 (34,500-631,500)

   CD4 lymphocyte count (cells/mm3)c

30 (13-103)

Organ failure status

 

   Mechanical ventilator use

106 (78.5)

   Shock (use of vasopressors > 24 hours)

49 (36.3)

   Renal replacement therapy

11 (8.1)

Time from hospitalization to ICU admission (days)

2 (0-9.0)

Laboratory data

 

   Albumin (g/dL)d

2.83 (2.40-3.40)

   LDH (units/L)e

966.5 (686.5-1446.25)

APACHE II score

19 (15-25)

in-ICU mortality

50 (37.0)

in-hospital mortality

66 (48.9)

  1. Values are given as median (interquartile) or number (%), unless otherwise indicated.
  2. aData were available for 49 patients with prior HAART at hospital admission.
  3. bData were available for 121 patients.
  4. cData were available for 129 patients.
  5. dData were available for 127 patients.
  6. eData were available for 114 patients.
  7. APACHE II, Acute Physiology and Chronic Health Evaluation II; HAART, highly active antiretroviral therapy; LDH, lactate dehydrogenase.