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Table 2 Bivariate association between perioperative factors, study variables and renal outcomesa

From: O2 delivery and CO2 production during cardiopulmonary bypass as determinants of acute kidney injury: time for a goal-directed perfusion management?

 

AKI stage 1

AKI stage 2

Any AKI

Variable

β coefficient

P value

β coefficient

P value

β coefficient

P value

Centre (1 or 2)

0.986

0.036b

2.034

0.001b

1.678

0.001b

Age (years)

0.049

0.011b

0.020

0.142

0.035

0.004b

Diabetes

0.762

0.057

0.346

0.345

0.611

0.037b

EuroSCORE

0.012

0.309

0.036

0.001b

0.034

0.001b

Reoperation

-18.9

0.998

1.313

0.003b

0.565

0.183

CABG and valve operation

0.709

0.085

1.103

0.001b

1.104

0.001b

CPB duration (minutes)

0.006

0.910

0.009

0.001b

0.008

0.005b

PRCs transfusion (U)

0.103

0.288

0.221

0.004b

0.206

0.002b

Lowest HCT during CPB

-0.075

0.147

-0.114

0.012b

-0.111

0.003b

Nadir DO2 (mL/minute/m2)

-0.005

0.198

-0.012

0.001b

-0.011

0.001b

Peak VCO2 (mL/minute/m2)

-0.052

0.014b

0.030

0.090

-0.005

0.743

Nadir DO2/VCO2 ratio

0.136

0.433

-0.408

0.010b

-0.192

0.119

  1. aAKI: acute kidney injury; β: regression coefficient; CABG: coronary artery bypass graft; CPB: cardiopulmonary bypass; HCT: hematocrit; PRCs: packed red blood cells; DO2: oxygen delivery; VCO2: carbon dioxide production; bstatistically significant P values.