Table 3 The level of ATP in sepsis

Critically ill septic patients and healthy subjects undergoing elective surgery

ATP (nmol/mg dry weight) in skeletal muscle biopsies:

Controls (8): 12.5 (9.7 to 13.7)

Survivors (12):15.8 (12.1 to 18.6)

Non-survivors (9): 7.6 (6.6 to 10.0) (P < 0.001)

Human umbilical vein endothelial cells incubated with healthy or septic sera

ATP (nmol/L) in the cells exposed to the serum of:

Controls: 13.5 ± 1.9

Septic shock patients: 6.7 ± 1.2 (P < 0.01)

Murine model of endotoxaemia (LPS-induced)

ATP (μmol/g wet weight) in liver:

Controls: 3.51 ± 0.21

Endotoxaemic: 3.00 ± 0.13 (P < 0.05)