Effects of discontinuing or continuing ongoing statin therapy in severe sepsis and septic shock: a retrospective cohort study

Table 5 Multivariable linear regression model for organ failure free days

	Coefficient (ß)	Standard error	95% confidence interval	Wald χ²	P value
Intercept	2589	1832
Statin continuation	2.24	1.36	(-0.43, 4.91)	2.71	0.10
SAPS II score at ICU admission	-0.10	0.03	(-0.16, -0.04)	9.26	<0.01
SOFA score at ICU admission	-0.37	0.27	(-0.90, 0.15)	1.93	0.17
Prior statin therapy duration	0.04	0.17	(-0.29, 0.36)	0.05	0.83
Surgery treatment before ICU admission	-1.30	1.64	(-4.52, 1.92)	0.62	0.43
Septic shock at ICU admission	1.90	1.75	(-1.53, 5.32)	1.18	0.28
Infection site	0.46	0.38	(-0.28, 1.19)	1.48	0.22
Polymicrobial infection	-3.46	1.55	(-6.49, -0.43)	5.01	0.03
Hospital-acquired infection	1.17	1.41	(-1.59, 3.94)	0.69	0.41
Low-dose corticosteroid treatment	-2.04	1.26	(-4.51, 0.44)	2.60	0.11
Year of ICU admission	-1.29	0.91	(-3.08, 0.51)	1.98	0.17

SAPS, simplified acute physiology score; SOFA, sequential organ failure assessment.

ISSN: 1364-8535