Table 3 Outcome of 76 patients with severe sepsis and septic shock according to discontinuation or not of ongoing statin therapy at ICU admission
Discontinuation group (n = 32) | Continuation group (n = 44) | P value | Odds ratio (95% CI) | |
|---|---|---|---|---|
Invasive mechanical ventilation, n (%) | 23 (72%) | 21 (48%) | 0.03 | 0.36 (0.14-0.94) |
Duration of invasive mechanical ventilation, days | 11 (4-18) | 6 (3-20) | 0.56 | |
Acute Respiratory Distress Syndrome, n (%) | 13 (41%) | 8 (18%) | 0.03 | 0.33 (0.12-0.92) |
Septic shock during ICU stay, n (%) | 24 (75%) | 23 (52%) | 0.04 | 0.37 (0.14-0.99) |
Organ failure free days* | 6 (0-12) | 11 (6-14) | 0.03 | |
Organ dysfunction free days* | 2 (0-10) | 10 (3-12) | 0.03 | |
Hemodynamic failure free days * | 11 (7-13) | 14 (10-14) | 0.04 | |
ICU length of stay, days (ICU survivors, n = 57) | 9 (4-16) | 6 (4-10) | 0.32 | |
Hospital length of stay, days (hospital survivors, n = 54) | 36 (18-54) | 24 (12-44) | 0.09 | |
ICU deaths, n (%) | 10 (31%) | 9 (21%) | 0.28 | 0.57 (0.20-1.61) |
Hospital deaths, n (%) | 13 (41%) | 9 (21%) | 0.06 | 0.38 (0.14-1.04) |