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Table 2 Crude OR of clinical and biochemical variables for death (GOS 1) in hospital and six months after severe traumatic brain injury using univariate logistic regression

From: Neuronal and glial markers are differently associated with computed tomography findings and outcome in patients with severe traumatic brain injury: a case control study

 

In HospitalMortality

6 months Mortality

Variable

OR (95%CI)

C

OR (95%CI)

C

UCH-L1

2.74 (1.54-4.90)*

0.74

2.29 (1.07-4.90)†

0.62

GFAP

1.41 (1.08-1.84)†

0.76

3.30 (1.21-8.50)†

0.75

Age

1.02 (0.99-1.05)

0.60

1.07 (1.03-2.11)*

0.78

GCS

0.64 (0.45-0.91)†

0.69

0.59 (0.41-0.85)†

0.72

Gender

    

   Female

Reference

 

Reference

 

   Male

1.01 (0.80-1.29)

0.60

0.69 (0.19-2.58)

0.53

Marshall Score

    

   I-II

Reference

 

Reference

 

   III-IV

9.80 (1.50-63.83)†

 

12 (1.58-91.08)†

 

   V-VI

2.80 (0.55-14.23)

0.67

5.56 (1.25-24.77)†

0.67

  1. C = The area under an receiver operating characteristic curve (also known as c-statistic) provides an overall measure of classification accuracy (representing the overall proportion of individuals correctly classified), with the value of one representing perfect accuracy.
  2. * P < 0.001, † P < 0.01
  3. GCS: Glasgow Coma Scale score; GFAP: glial fibrillary acidic protein; GOS: Glasgow Outcome Scale; OR: odds ratios; UCH-L1: Ubiquitin C-terminal Hydrolase-L1 protein.