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Table 1 Data for selected parameters while patients were ventilated with PCV-IRV or APRV

From: Airway pressure release ventilation increases cardiac performance in patients with acute lung injury/adult respiratory distress syndrome

Parameter PCV-IRV APRV P
Pawpk (cmH2O) 38 ± 3 25 ± 3 <0.01
Pawmean (cmH2O) 18 ± 3 12 ± 2 <0.01
Paralytics (% of patients) 74 4 <0.01
Sedative use (% of PCV patients) 100 68 <0.01
Pressors (% of patients) 92 45 <0.01
Lactate (mmol/l) 2.2 ± 0.4 1.8 ± 0.3 <0.01
Cardiac index (l/min/m2) 3.2 ± 0.4 4.6 ± 0.3 <0.01
DO2 (ml/min) 997 ± 108 1409 ± 146 <0.01
SvO2 (%) 72 ± 4 80 ± 5 0.22
CVP (mmHg) 18 ± 4 12 ± 5 <0.01
Urine output (cc/kg per h) 0.83 ± 0.2 0.96 ± 0.3 <0.01
  1. Values are means ± SD, or percentage, as indicated. Mean values were compared by two-tailed t-test, whereas percentages were evaluated using Χ2 tests. CVP, central venous delivery; DO2, oxygen delivery; Pawmean, mean airway pressure; Pawpk, peak airway pressure.