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Table 1 Data for selected parameters while patients were ventilated with PCV-IRV or APRV

From: Airway pressure release ventilation increases cardiac performance in patients with acute lung injury/adult respiratory distress syndrome

Parameter

PCV-IRV

APRV

P

Pawpk (cmH2O)

38 ± 3

25 ± 3

<0.01

Pawmean (cmH2O)

18 ± 3

12 ± 2

<0.01

Paralytics (% of patients)

74

4

<0.01

Sedative use (% of PCV patients)

100

68

<0.01

Pressors (% of patients)

92

45

<0.01

Lactate (mmol/l)

2.2 ± 0.4

1.8 ± 0.3

<0.01

Cardiac index (l/min/m2)

3.2 ± 0.4

4.6 ± 0.3

<0.01

DO2 (ml/min)

997 ± 108

1409 ± 146

<0.01

SvO2 (%)

72 ± 4

80 ± 5

0.22

CVP (mmHg)

18 ± 4

12 ± 5

<0.01

Urine output (cc/kg per h)

0.83 ± 0.2

0.96 ± 0.3

<0.01

  1. Values are means ± SD, or percentage, as indicated. Mean values were compared by two-tailed t-test, whereas percentages were evaluated using Χ2 tests. CVP, central venous delivery; DO2, oxygen delivery; Pawmean, mean airway pressure; Pawpk, peak airway pressure.