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Table 1 Diagnostic value of ABGA parameters to identify disorders responsible for acute dyspnea (only significant variables)

From: Value of arterial blood gas analysis in patients with acute dyspnea: an observational study

 

Variable

OR (95% CI)

AUC

(95% CI)

Acute heart failure

pH

0.58 (0.44-0.77)

0.615

(0.57-0.66)

 

PaCO2

0.81 (0.69-0.95)

 

Exacerbated COPD or asthma

pH

1.64 (1.14-2.37)

0.670

(0.63-0.71)

 

PaCO2

1.44 (1.20-1.73)

 
 

Hypoxemia

1.71 (1.04-2.82)

 

Pulmonary embolism

PaCO2

0.61 (0.44-0.85)

0.678

(0.64-0.72)

Pneumonia or bronchitis

Hypoxemia

1.84 (1.07-3.17)

0.558

(0.51-0.60)

Anxiety disorder

pH

4.50 (2.27-8.92)

0.855

(0.82-0.88)

 

Hypoxemia

0.21 (0.07-0.65)

 

Pulmonary disorder

pH

1.40 (1.06-1.87)

0.639

(0.60-0.66)

 

PaCO2

1.31 (1.12-1.54)

 
 

Hypoxemia

2.01 (1.37-3.13)

 
  1. Multivariable logistic regression analysis. Odds ratios (OR) with 95% confidence interval (95% CI) for independent arterial blood gas analysis (ABGA) parameters; Categorial variables included in the model were hypoxemia, metabolic acidosis or alkalosis, respiratory acidosis or alkalosis, mixed-type alkalosis or acidosis, pH, partial pressure of arterial carbon dioxide (PaCO2), and partial pressure of arterial oxygen (PaO2). OR are given for any increase of 1 kPa for PaO2 or PaCO2, and 0.1 for pH. Area under the curve (AUC) quantifying the diagnostic accuracy of the individual variables in settings with only one significant diagnostic ABGA variable (pulmonary embolism and community-acquired pneumonia), and for the optimal combination of ABGA variables in settings with more than one significant variables (all others). COPD, chronic obstructive pulmonary disease.
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Critical Care

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