Table 3 Probability of time the concentration is four times MIC attainment for Pseudomonas spp.
Antibiotic, daily dose (number of patients) | Time period (number of series) | PK/PD target attainment (number of series (%)) |
|---|---|---|
MEM 1 g twice daily (n = 17) | All (n = 22) | 18 (81%) |
Day < 48 hours (n = 7) | 5 (71%) | |
Days > 48 hours (n = 15) | 13 (87%) | |
TZP 4 g four times daily (n = 16) | All (n = 21) | 15 (71%) |
Day < 48 hours (n = 12) | 8 (66%) | |
Days > 48 hours (n = 9) | 7 (78%) | |
FEP 2 g twice daily (n = 8) | All (n = 11) | 0 (0%) |
Day < 48 hours (n = 7) | 0 (0%) | |
Days > 48 hours (n = 4) | 0 (0%) | |
CAZ 2 g twice daily (n = 12) | All (n = 15) | 8 (53%) |
Day < 48 hours (n = 8) | 3 (38%) | |
Days > 48 hours (n = 7) | 5 (71%) |