Table 4 Diagnostic value of the various parameters studied

From: Meningitis in adult patients with a negative direct cerebrospinal fluid examination: value of cytochemical markers for differential diagnosis

	CSF parameters				Serum parameters		CSF/serum ratio
	Neutrophil/mm³	Protein g/L	Glucose mmol/L	Lactate mmol/L	PCT ng/ml	CRP mg/l	Glucose CSF/serum	Lactate CSF/serum
AUC	0.86	0.93	0.69	0.96	0.99	0.92	0.87	0.84
[CI 95%]	[0.86-0.94]	[0.92-0,98]	[0.69-0.76]	[0.95-1]	[0.99-1]	[0.92-0.98]	[0.86-0.91]	[0.84-0.93]
Optimal cut-point	118	1.88	2.2	3.8	0.28	37	0.48	2.22
Sensitivity	0.80	0.89	0.97	0.94	0.97	0.86	0.84	0.79
Specificity	0.85	0.93	0.49	0.97	1	0.84	0.89	0.89
Positive predictive value	0.47	0.67	0.92	0.82	0.97	0.46	0.98	0.52
Negative predictive value	0.96	0.98	0.71	0.99	1	0.97	0.66	0.97
Global value	0.84	0.92	0.90	0.96	0.99	0.84	0.76	0.87

AUC, area under a curve; CI, confidence interval; CSF, cerebrospinal fluid.

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