Table 1 Baseline patients' characteristics and comparison between neutropenic and non-neutropenic patients
From: C-reactive protein in critically ill cancer patients with sepsis: influence of neutropenia
All Patients | Neutropenic | Non neutropenic | P-value | |
|---|---|---|---|---|
N | 154 | 86 | 68 | |
Age (yrs) | 48.5 ± 18.1 | 47.0 ± 17.8 | 50.4 ± 18.4 | 0.248 |
Gender (M/F) | 94/60 | 54/32 | 40/28 | 0.622 |
Type of cancer | 0.569 | |||
Solid | 49 | 29 | 20 | |
Hematologic | 105 | 57 | 48 | |
Previous radiotherapy | 36 | 21 | 15 | 0.731 |
Previous Chemotherapy | 112 | 72 | 40 | 0.001 |
Previous surgery | 6 | 1 | 5 | 0.049 |
Non-invasive Ventilation | 15 | 14 | 1 | 0.002 |
Invasive mechanical Ventilation | 135 | 74 | 61 | 0.493 |
Vasopressors | 112 | 62 | 50 | 0.842 |
Type of infection | 0.007 | |||
Pneumonia | 63 | 28 | 35 | |
Peritonitis | 15 | 7 | 8 | |
Urinary | 3 | 0 | 3 | |
Blood stream infections | 8 | 4 | 4 | |
Skin/Soft tissue infections | 7 | 4 | 3 | |
CNS infections | 1 | 0 | 1 | |
Other infections | 57 | 43 | 14 | |
SAPS II (points) | 62.2 ± 16.8 | 62.2 ± 16.7 | 62.5 ± 16.8 | 0.827 |
SOFA (Day 1) (points) | 11.4 ± 3.9 | 11.6 ± 4.1 | 11.2 ± 4.1 | 0.591 |
Sepsis severity | 0.899 | |||
Sepsis | 10 (6.5%) | 6 (7%) | 4 (5.9%) | |
Severe sepsis | 29 (18.8%) | 17 (19.8%) | 12 (17.6%) | |
Septic shock | 111 (74.7%) | 63 (73.3%) | 52(76.5%) | |
Total white cell count (/mm3) | 1,400 (14,636) | 352 (909) | 22,100 (35,900) | < 0.001 |
Temperature (°C) | 37.0 ± 1.5 | 37.2 ± 1.5 | 36.8 ± 1.5 | 0.119 |
CRP (Day 1) (mg/dL) | 23.6 ± 11.6 | 25.9 ± 11.2 | 19.7 ± 11.4 | 0.009 |
Duration of mechanical ventilation (days) | 6.0 (9.0) | 6.0 (8.0) | 6.0 (9.0) | 0.616 |
ICU length of stay (days) | 7.0 (10.3) | 7.0 (12.0) | 8.0 (10.0) | 0.699 |
Hospital length of stay (days) | 18.5 (23.6) | 20.5 (25.0) | 16.5 (21.0) | 0.111 |
ICU mortality | 111 (72.1%) | 60 (69.8%) | 51 (75.0%) | 0.472 |
Hospital mortality | 122 (79.2%) | 65 (75.6%) | 57 (83.8%) | 0.211 |