High-dose tranexamic acid reduces blood loss in postpartum haemorrhage

Table 2 PPH management^a

Group	TA	Control	P value
Number of patients	72	72
Mean crystalloid loading at T3, mL (± SD)	934 (575)	949 (712)	0.54
Mean colloid loading at T3, mL (± SD)	611 (500)	736 (459)	0.13
Mean total loading volume, mL, (± SD)	1,547 (722)	1,672 (787)	0.36
Prostaglandins for PPH, n (%)	36 (48)	34 (43)	0.74
Postpartum thromboprophylaxis, n (%)	16 (22)	14 (20)	0.8

^aPPH, postpartum haemorrhage; TA, tranexamic acid; T3, 2 hours after inclusion. α risk: P < 0.05 using the χ² test or Fisher's exact test for categorical variables. Student's t-test was used in cases of normal distribution, and otherwise the Mann-Whitney U test was used for numerical variables.

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