Characteristic | Ultrasound examinationb | Modified Boston criteria scoring | NT-proBNP | Ultrasound examination + NT-proBNPc | P valued |
---|---|---|---|---|---|
Sensitivity | 100% (95% CI 98 to 100) | 85% (95% CI 79 to 89) | 92% (95% CI 88 to 95) | 100% (95% CI 98 to 100) | < 0.01 |
Specificity | 95% (95% CI 91 to 100) | 86% (95% CI 82 to 90) | 89% (95% CI 84 to 92) | 100% (95% CI 97 to 100) | < 0.01 |
NPV | 100% (95% CI 98 to 100) | 80% (95% CI 77 to 85) | 86% (95% CI 82 to 90) | 100% (95% CI 98 to 100) | < 0.01 |
PPV | 96% (95% CI 93 to 100) | 90% (95% CI 86 to 93) | 90% (95% CI 85 to 94) | 100% (95% CI 96 to 100) | < 0.01 |
LR+ | 20 (95% CI 1.98 to 89.94) | 6.1 (95% CI 1.65 to 18.48) | 8.36 (95% CI 1.72 to 33.86) | Infinite | < 0.01 |
LR- | 0 | 0.18 (95% CI 0.07 to 0.52) | 0.09 (95% CI 0.02 to 0.23) | 0 | < 0.01 |
AUROC | 0.94 (95% CI: 0.90 to 0.97) | 0.86 (95% CI 0.80 to 0.91) | 0.90 (95% CI 0.84 to 0.94) | 0.99 (95% CI 0.98 to 1.00) | < 0.01 |