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Figure 2 | Critical Care

Figure 2

From: Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients

Figure 2

TLR4 / TLR2 polymorphisms and time course of perioperative serum concentrations of IL-8 (a), IL-10 (b) and GM-CSF (c). Sampling times: A: preoperative, B: postoperative at day of surgery, C: postoperative Day 1. GM-CSF, granulocyte macrophage-colony stimulating factor; IL, interleukin; TLR2 SNP, toll-like receptor 2 single-nucleotide polymorphism carrier; TLR4 SNP, toll-like receptor 4 single-nucleotide polymorphism carrier. Number of patients in each group: non-carrier = 274, TLR4 SNP = 51, TLR2 SNP = 13. Values are shown as mean and 95% confidence intervals. *P < 0.05 compared to A; †P < 0.05 compared to B; ‡P < 0.05 compared to non-carrier.

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Critical Care

ISSN: 1364-8535