Table 1 Main characteristics of the patients at the time of inclusion^a

Age, yr

Sex, male/female

SAPS II score

Main diagnosis at admission, n

   Septic shock

   Acute respiratory failure

   Other

Delay between admission and study inclusion, n (%)

   <24 hours

   24 to 48 hours

   >48 hours

Ramsay score 5 versus 6, n

Responders using 10% versus 15% CO change to define fluid responsiveness, n (%)

Arterial lactate concentration, mM/l (n = 61)

Arterial lactate concentration >2.5 mM/l, n (%)

Urine output during the past hour, ml/kg

Urine output during the last hour <0.5 ml/kg, n (%)

Skin mottling, n (%)

Catecholamine infusion, n (%)

   Norepinephrine, μg/kg/min (n = 53)

   Epinephrine, μg/kg/min (n = 10)

   Dobutamine, μg/kg/min (n = 20)

CO measured by PiCCO™/versus pulmonary artery catheter, n (%)

Arterial catheter site, femoral versus radial, n (%)

PEEPt, cmH₂O

Plateau pressure, cmH₂O

Driving pressure (plateau pressure - PEEPt cmH₂O)

Alveolar to vascular pressure transmission index (n = 33) [20]

Respiratory changes in PAOP, mmHg (n = 33)

Tidal volume, ml

Tidal volume indexed to measured versus predicted body weight, ml/kg

Respiratory system static compliance, ml/cmH₂O

RR, cycles/minute

HR:RR ratio

I:E ratio, %

PaO₂:FiO₂ ratio, mmHg