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Table 1 Main characteristics of the patients at the time of inclusiona

From: Respiratory pulse pressure variation fails to predict fluid responsiveness in acute respiratory distress syndrome

Patient characteristic Data
Age, yr 59 ± 15
Sex, male/female 45/20
SAPS II score 56 ± 19
Main diagnosis at admission, n  
   Septic shock 28
   Acute respiratory failure 12
   Other 25
Delay between admission and study inclusion, n (%)  
   <24 hours 42 (65%)
   24 to 48 hours 12 (18%)
   >48 hours 11 (17%)
Ramsay score 5 versus 6, n 14 versus 51
Responders using 10% versus 15% CO change to define fluid responsiveness, n (%) 26 (40%) versus 21 (32%)
Arterial lactate concentration, mM/l (n = 61) 3.0 ± 2.5
Arterial lactate concentration >2.5 mM/l, n (%) 25 (38%)
Urine output during the past hour, ml/kg 0.8 ± 0.8
Urine output during the last hour <0.5 ml/kg, n (%) 22 (34%)
Skin mottling, n (%) 22 (34%)
Catecholamine infusion, n (%) 59 (91%)
   Norepinephrine, μg/kg/min (n = 53) 0.76 ± 0.88
   Epinephrine, μg/kg/min (n = 10) 0.59 ± 0.49
   Dobutamine, μg/kg/min (n = 20) 13 ± 10
CO measured by PiCCO™/versus pulmonary artery catheter, n (%) 32 (49%)/33 (51%)
Arterial catheter site, femoral versus radial, n (%) 51 (78%)/14 (22%)
PEEPt, cmH2O 8.5 ± 3.2
Plateau pressure, cmH2O 21.2 ± 5.0
Driving pressure (plateau pressure - PEEPt cmH2O) 13.7 ± 4.1
Alveolar to vascular pressure transmission index (n = 33) [20] 0.39 ± 0.17
Respiratory changes in PAOP, mmHg (n = 33) 4.8 ± 2.0 (range, 2 to 9)
Tidal volume, ml 457 ± 67
Tidal volume indexed to measured versus predicted body weight, ml/kg 6.5 ± 1.4 versus 6.9 ± 0.95
Respiratory system static compliance, ml/cmH2O 40.4 ± 15.8
RR, cycles/minute 24 ± 6
HR:RR ratio 4.5 ± 1.6
I:E ratio, % 31 ± 6
PaO2:FiO2 ratio, mmHg 136 ± 50
  1. aSAPS, simplified acute physiology score II; CO, cardiac output; PEEPt; total positive end-expiratory pressure; PAOP, pulmonary artery occlusion pressure; I:E, inspiration length:expiration length ratio. HR:RR, heart rate:respiratory rate ratio.
  2. Quantitative variables are expressed as mean ± SD.