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Table 4 Comparison of severity-of-illness index in patients with negative culturesa

From: Impact of de-escalation therapy on clinical outcomes for intensive care unit-acquired pneumonia

Severity index De-escalation group (N= 12) Non-de-escalation group (N= 16) P value
Mean baseline APACHE II score (±SD) 15.36 ± 5.9 16.56 ± 6.6 0.63
Mean baseline CPIS (±SD) 6.83 ± 1.2 6.56 ± 0.9 0.50
5-day APACHE II score (±SD) 11.70 ± 5.0 13.82 ± 3.3 0.26
   Category 1, n (%) 11 of 12 (91.7%) 14 of 16 (87.5%) 0.90
   Category 2, n (%) 1 of 12 (8.3%) 2 of 16 (12.5%)  
Mean 5-day CPIS (±SD) 5.9 ± 1.1 6.5 ± 1.2 0.23
   Category 1, n (%) 9 of 12 (75%) 8 of 16 (50%) 0.13
   Category 2, n (%) 3 of 12 (25%) 8 of 16 (50%)  
  1. aAPACHE II, Acute Physiology and Chronic Health Evaluation II; CPIS, Clinical Pulmonary Infection Score.