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Table 4 Comparison of severity-of-illness index in patients with negative culturesa

From: Impact of de-escalation therapy on clinical outcomes for intensive care unit-acquired pneumonia

Severity index

De-escalation group (N= 12)

Non-de-escalation group (N= 16)

P value

Mean baseline APACHE II score (±SD)

15.36 ± 5.9

16.56 ± 6.6

0.63

Mean baseline CPIS (±SD)

6.83 ± 1.2

6.56 ± 0.9

0.50

5-day APACHE II score (±SD)

11.70 ± 5.0

13.82 ± 3.3

0.26

   Category 1, n (%)

11 of 12 (91.7%)

14 of 16 (87.5%)

0.90

   Category 2, n (%)

1 of 12 (8.3%)

2 of 16 (12.5%)

 

Mean 5-day CPIS (±SD)

5.9 ± 1.1

6.5 ± 1.2

0.23

   Category 1, n (%)

9 of 12 (75%)

8 of 16 (50%)

0.13

   Category 2, n (%)

3 of 12 (25%)

8 of 16 (50%)

 
  1. aAPACHE II, Acute Physiology and Chronic Health Evaluation II; CPIS, Clinical Pulmonary Infection Score.