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Table 3 Characteristics of studies included in meta-analysis

From: A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis

Author: Year Study design Population Modality Early (n) Late (n) Early criteria Late criteria
Bouman [10] 2002 Randomised Cardiac surgery/medical CVVH 35 36 RRT within 12 hours if Urine Output <30 ml/hr Urea >40 mmol/l or K >6.5 mmol/L
Sugahara [32] 2004 Randomised Cardiac Surgery CVVH 14 14 Urine Output <20 ml/hr Urine Output <30 cc/hr
Liu [21] 2006 Prospective Cohort Medical,Surgery CRRT/IHD 122 121 Urea <27.1 mmol/L Urea >27.1 mmol/L
Sabater [33] 2008 Prospective Cohort Medical (Septic Shock) CVVHF 9 23 Rifle Criteria (Risk, Injury)* Rifle Criteria (Failure)**
Bagshaw [34] 2009 Prospective Cohort Medical, Surgical CRRT/IHD 618 619 Urea <24.2 mmol/L Urea >24.2 mmol/L
Bagshaw [35] 2010 Prospective Cohort Medical, Surgical CRRT/IHD 117 117 Urea <23 mmol/L Urea >23 mmol/L
Gettings [15] 1999 Retrospective Cohort Trauma CAVHD and CVVHD 41 59 Urea <21.4 mmol/L Urea >21.4 mmol/L
Elahi [38] 2004 Retrospective Cohort Cardiac surgery CVVH 28 36 Urine Output <100 cc in 8 hrs K >6 mmol/L, Cr >250 mmol/L
Dermirkilic [13] 2004 Retrospective Cohort Cardiac Surgery CVVHDF 27 34 Cr >400 μmol/L, Potassium >5.5 mmol/L Oliguria
Andrade [36] 2007 Retrospective Cohort Medical (ARDS/Sepsis) IHD/SLED 18 15 On admission At 24 hours
Wu [42] 2007 Retrospective Cohort Surgical ALF IHD/CVVH 54 26 Urea < 28.6 mmol/L Urea >28.6 mmol/L
Manche [40] 2008 Retrospective Cohort Cardiac Surgery IHD 56 15 Hyperkalemia U/O <0.5 ml/kg/hour
Iyem [39] 2009 Retrospective Cohort Cardia Surgery CVVH 95 90 RRT on admission After 48 hours when anuric
Shiao [41] 2009 Retrospective Cohort Surgery/Trauma CVVH 51 47 Rifle Criteria (Risk)* Rifle Injury, Failure**
Carl [37] 2010 Retrospective Cohort Medical (sepsis) CRRT/IHD 85 62 Urea <35.7 mmol/l Urea >35.7 mmol/L
  1. Abbreviations: Cr = creatinine (μmol/L); K = potassium (mmol/L).
  2. RIFLE Criteria Risk: Increase in serum Creatinine by 1.5 times or urine output <0.5 ml/kg/hour × 6 hours.
  3. RIFLE Criteria Injury: Increase in serum Creatinine by 2 times or urine output <0.5 ml/kg/hour × 12.
  4. RIFLE Criteria Failure: Increase in serum Creatinine by 3 times or urine output <0.3 ml/kg/hour × 24.