Balanced massive transfusion ratios in multiple injury patients with traumatic brain injury

Table 2 Fluids and blood products transfused during initial resuscitation^a

	AIS score, head <3			AIS score, head ≥3
Transfusions and time intervals	FFP:pRBC ratio ≤1:2	FFP:pRBC ratio >1:2	P value	FFP:pRBC ratio ≤1:2	FFP:pRBC ratio >1:2	P value
Fluids prehospital
Mean crystalloids, ml (±SD)	1,491 ± 937	1,391 ± 819	0.433	1,354 ± 888	1,297 ± 743	0.981
Mean colloids, ml (±SD)	991 ± 615	939 ± 579	0.272	982 ± 654	945 ± 475	0.957
Fluids emergency room
Mean crystalloids, ml (±SD)	3,549 ± 2,858	3,981 ± 2,959	0.071	3,122 ± 2,640	4,000 ± 3,036	<0.001
Mean colloids, ml (±SD)	1,648 ± 1,478	1,802 ± 1,592	0.080	1,568 ± 1,247	1,788 ± 1,371	0.112
Mean pRBC transfusion, n (±SD)	19.5 ± 11.2	19.5 ± 11.9	0.916	18.4 ± 9.8	18.9 ± 10.7	0.980
Mean FFP transfusion, n (±SD) (min-max)	5.7 ± 5.2 (0 to 32)	18.0 ± 12.3 (6 to 88)	<0.001	5.5 ± 4.8 (0 to 30)	17.8 ± 10.4 (6 to 84)	<0.001
Mean minutes from trauma scene to ER (±SD)	59 (±39)	64 (±40)	0.115	66 (±44)	69 (±44)	0.464
Mean minutes from hospital admission including ER and operation theater to ICU transfer (±SD)	303 (±144)	350 (±140)	<0.001	290 (±147)	337 (±143)	0.001

^aAIS, Abbreviated Injury Scale; FFP, fresh frozen plasma; pRBC, packed red blood cell; SD, standard deviation; ER, emergency room; ICU, intensive care unit.

ISSN: 1364-8535