Figure 2From: Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patientsSerum suPAR concentrations and predictive power for sepsis at ICU admission. (A) In patients with sepsis suPAR serum concentrations were significantly (P < 0.001, U-test) higher as compared with patients with non-septic etiology of critical illness. (B) Receiver operating characteristic (ROC) curve analyses comparing the diagnostic power in predicting sepsis of suPAR (black line, area under the curve = AUC 0.615) with classical markers of inflammation and bacterial infection, C-reactive protein (CRP; grey line, AUC 0.857), procalcitonin (PCT; dotted black line, AUC 0.780) and white blood cell count (leukocytes; dotted grey line, AUC 0.564).Back to article page