Table 1 Baseline clinical and laboratory characteristics of subjects
| Â | All | Survivors | Non-survivors | P-value |
|---|---|---|---|---|
Patients, No. | 576 | 445 | 131 | / |
Male (%) | 55.7 | 57.8 | 58.0 | 1.000 |
Age (years) | 71.5 ± 16.5 | 70.5 ± 16.0 | 74.9 ± 14.3 | 0.004 |
Principal diagnosis leading to ICU admission (%) | Â | Â | Â | Â |
   Pulmonary disease | 32.4 | 35.1 | 23.7 | 0.015 |
   Cardiovascular disease | 36.9 | 37.8 | 34.3 | 0.537 |
   Neurologic disease | 7.1 | 6.1 | 10.7 | 0.082 |
   Digestive disease | 5.6 | 6.1 | 3.8 | 0.391 |
   Renal insufficiency | 1.9 | 2.2 | 0.7 | 0.270 |
   Poisoning | 3.3 | 3.8 | 1.5 | 0.470 |
   Infectious disease/sepsis | 5.6 | 2.7 | 15.2 | < 0.001 |
   Other | 7.1 | 6.3 | 9.9 | 0.175 |
Hypertension (%) | 58.0 | 58.7 | 55.7 | 0.548 |
Diabetes mellitus (%) | 25.9 | 24.7 | 29.8 | 0.257 |
Accompanying infection (%) | 41.9 | 42.9 | 45.0 | 0.035 |
Systolic pressure (mmHg) | 124.9 ± 22.4 | 127.4 ± 21.2 | 116.8 ± 24.7 | < 0.001 |
Diastolic pressure (mmHg) | 68.0 ± 12.2 | 69.3 ± 11.6 | 63.9 ± 13.3 | < 0.001 |
Heart rate (bpm) | 91.0 ± 20.5 | 89.2 ± 19.1 | 97.3 ± 24.0 | < 0.001 |
Fasting plasma glucose (mmol/L) | 11.4 ± 6.3 | 7.12 ± 2.9 | 8.5 ± 4.3 | < 0.001 |
White blood cell (109/L) | 7.4 ± 3.4 | 10.8 ± 5.6 | 13.5 ± 7.9 | < 0.001 |
Hemoglobin (g/L) | 116.3 ± 25.4 | 118.7 ± 24.0 | 108.1 ± 28.1 | < 0.001 |
eGFR(mL/min/1.73 m2) | 58.0 (6.5 to 150.0) | 62.6 (14.5 to 30.2) | 34.8 (8.2 to 108.7) | < 0.001 |
APACHE-II score (points) | 13.6 ± 7.1 | 11.7 ± 5.6 | 19.9 ± 7.5 | < 0.001 |
NT-proBNP (ng/ml) | 2,922 (103 to 35,000) | 5,996 (6 to 35,000) | 12,726 (59 to 35,000) | < 0.001 |
CRP(mg/L) | 39.8 (7.9 to 158.5) | 56.7 (1.0 to 160.1) | 85.9 (6.0 to 160.2) | < 0.001 |