Table 6 Bleeding and coagulation.
HES 130/0.4(n = 100) | NaCl 0.9%(n = 96) | P value | |||
|---|---|---|---|---|---|
Number of patients with RBC transfusions, n (%) | 29 (29.0) | 20 (20.8) | 0.2480 | ||
Volume (ml) of RBC transfusions, n (mean ± SD, range) | 100 (214 ± 358, 0 to 1,394) | 96 (165 ± 354, 0 to 1,661) | 0.3415 | ||
Blood loss, ml, including blood sampling and drainage, n (mean ± SD, range) | 63 (10.0 ± 24.4, 0.4 to 150.7) | 65 (10.5 ± 29.4, 0.2 to 207.8) | NS | ||
Coagulation parameters, median values over time | INR | aPTT (ratio) | INR | aPTT (ratio) | P value |
Baseline | 1.3 | 1.2 | 1.3 | 1.2 | |
Until HDSa | 0.1 | 0.2 | 0.0 | 0.1 | |
Day 1 | 0.0 | 0.1 | 0.0 | 0.1 | |
Day 2 | -0.1 | 0.1 | -0.1 | 0.0 | |
Day 3 | -0.1 | 0.1 | -0.2 | 0.0 | |
Day 4 | -0.2 | 0.1 | -0.2 | -0.1 | |
Day 5 | -0.1 | 0.0 | -0.1 | -0.1 | |
Day 8b | -0.1 | 0.0 | -0.2 | 0.0 | |
Lastc | -0.1 | 0.0 | -0.2 | 0.0 | |