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Citation: Critical Care 2023 27:365
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Heterogeneity in defining multiple trauma: a systematic review of randomized controlled trials
While numerous randomized controlled trials (RCTs) have been conducted in the field of trauma, a substantial portion of them are yielding negative results. One potential contributing factor to this trend could...
Citation: Critical Care 2023 27:363 -
Spinal cord perfusion pressure correlates with breathing function in patients with acute, cervical traumatic spinal cord injuries: an observational study
This study aims to determine the relationship between spinal cord perfusion pressure (SCPP) and breathing function in patients with acute cervical traumatic spinal cord injuries.
Citation: Critical Care 2023 27:362 -
Variables influencing the prediction of fluid responsiveness: a systematic review and meta-analysis
Prediction of fluid responsiveness in acutely ill patients might be influenced by a number of clinical and technical factors. We aim to identify variables potentially modifying the operative performance of flu...
Citation: Critical Care 2023 27:361 -
Beta-blockers in refractory hypoxemia on venovenous extracorporeal membrane oxygenation: a double-edged sword
Citation: Critical Care 2023 27:360 -
Non-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP) in patients with acute exacerbation of COPD: From the French OUTCOMEREA cohort
Non-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP), a nosocomial pneumonia that is not related to invasive mechanical ventilation (IMV), has been less studied than ventilator-associated pneumonia, an...
Citation: Critical Care 2023 27:359 -
Effect of corticosteroids on mortality in patients with community-acquired pneumonia
Citation: Critical Care 2023 27:358 -
Blood purification in critically ill patients: not enough, but still helpful
Citation: Critical Care 2023 27:357 -
Anticoagulant-related bleeding in patients receiving anticoagulant therapy over 10 years
Citation: Critical Care 2023 27:356 -
Recommendations on palliative care aspects in intensive care medicine
The timely integration of palliative care is important for patients suffering from various advanced diseases with limited prognosis. While a German S-3-guideline on palliative care exists for patients with inc...
Citation: Critical Care 2023 27:355 -
Prevention of cardiac surgery-associated acute kidney injury: a systematic review and meta-analysis of non-pharmacological interventions
Cardiac surgery-associated acute kidney injury (CSA-AKI) is frequent. While two network meta-analyses assessed the impact of pharmacological interventions to prevent CSA-AKI, none focused on non-pharmacologica...
Citation: Critical Care 2023 27:354 -
Hyperchloremia, a necessary evil in neurocritical care
Citation: Critical Care 2023 27:353 -
Is handheld video microscopy really the future of microcirculation monitoring?
Citation: Critical Care 2023 27:352 -
Outcome assessment for out-of-hospital cardiac arrest patients in Singapore and Japan with initial shockable rhythm
Singapore and Osaka in Japan have comparable population sizes and prehospital management; however, the frequency of ECPR differs greatly for out-of-hospital cardiac arrest (OHCA) patients with initial shockabl...
Citation: Critical Care 2023 27:351 -
Does AI's touch diminish the artistry of scientific writing or elevate it?
Citation: Critical Care 2023 27:350 -
Out-of-hospital cardiac arrest in children: an epidemiological study based on the German Resuscitation Registry identifying modifiable factors for return of spontaneous circulation
This work provides an epidemiological overview of out-of-hospital cardiac arrest (OHCA) in children in Germany between 2007 and 2021. We wanted to identify modifiable factors associated with survival.
Citation: Critical Care 2023 27:349 -
Comments on “Efficacy and safety of adjunctive corticosteroids in the treatment of severe community-acquired pneumonia: a systematic review and meta-analysis of randomized controlled trials”
Citation: Critical Care 2023 27:348 -
Hyperferritinemic sepsis, macrophage activation syndrome, and mortality in a pediatric research network: a causal inference analysis
One of five global deaths are attributable to sepsis. Hyperferritinemic sepsis (> 500 ng/mL) is associated with increased mortality in single-center studies. Our pediatric research network’s objective was to o...
Citation: Critical Care 2023 27:347 -
Prospective, multicenter validation of the deep learning-based cardiac arrest risk management system for predicting in-hospital cardiac arrest or unplanned intensive care unit transfer in patients admitted to general wards
Retrospective studies have demonstrated that the deep learning-based cardiac arrest risk management system (DeepCARS™) is superior to the conventional methods in predicting in-hospital cardiac arrest (IHCA). T...
Citation: Critical Care 2023 27:346 -
Drug diluent and efficacy of methylene blue in septic shock: authors’ reply
Citation: Critical Care 2023 27:345 -
Impact of Covid-19 on risk of severe maternal morbidity
We examined the risk of severe life-threatening morbidity in pregnant patients with Covid-19 infection.
Citation: Critical Care 2023 27:344 -
Advanced respiratory mechanics assessment in mechanically ventilated obese and non-obese patients with or without acute respiratory distress syndrome
Respiratory mechanics is a key element to monitor mechanically ventilated patients and guide ventilator settings. Besides the usual basic assessments, some more complex explorations may allow to better charact...
Citation: Critical Care 2023 27:343 -
Final approval for corticosteroids in severe CAP? For sure, in septic shock
Citation: Critical Care 2023 27:342 -
Acute kidney injury in neurocritical care
Approximately 20% of patients with acute brain injury (ABI) also experience acute kidney injury (AKI), which worsens their outcomes. The metabolic and inflammatory changes associated with AKI likely contribute...
Citation: Critical Care 2023 27:341 -
Long-term immunosuppressive treatment is not associated with worse outcome in patients hospitalized in the intensive care unit for septic shock: the PACIFIC study
Except in a few retrospective studies mainly including patients under chemotherapy, information regarding the impact of immunosuppressive therapy on the prognosis of patients admitted to the intensive care uni...
Citation: Critical Care 2023 27:340 -
Brain tissue oxygen monitoring in traumatic brain injury: part I—To what extent does PbtO2 reflect global cerebral physiology?
The primary aim was to explore the association of global cerebral physiological variables including intracranial pressure (ICP), cerebrovascular reactivity (PRx), cerebral perfusion pressure (CPP), and deviati...
Citation: Critical Care 2023 27:339 -
Transcutaneous electrical diaphragmatic stimulation in mechanically ventilated patients: a randomised study
Few specific methods are available to reduce the risk of diaphragmatic dysfunction for patients under mechanical ventilation. The number of studies involving transcutaneous electrical stimulation of the diaphr...
Citation: Critical Care 2023 27:338 -
Methylene blue as adjunctive therapy in septic shock: correct drug diluent derives optimal efficacy
Citation: Critical Care 2023 27:337 -
Effects of corticosteroids on severe community-acquired pneumonia: a closer look at the evidence
Citation: Critical Care 2023 27:336 -
Comment on: Association between intrarenal venous flow from Doppler ultrasonography and acute kidney injury in patients with sepsis in critical care: a prospective, exploratory observational study
Citation: Critical Care 2023 27:335 -
Authors’ reply to the comment from Glass et al.
Citation: Critical Care 2023 27:334 -
Artificial intelligence: a new editor limiting self-citation malpractice
Citation: Critical Care 2023 27:333 -
Use of dexmedetomidine in critical-ill patients: is it time to look to the actual evidence?
Citation: Critical Care 2023 27:332 -
FX06 to rescue SARS-CoV-2-induced acute respiratory distress syndrome: a randomized clinical trial
Vascular leakage is a major feature of acute respiratory distress syndrome (ARDS). We aimed to evaluate the efficacy of FX06, a drug under development that stabilizes interendothelial cell junctions, at reduci...
Citation: Critical Care 2023 27:331 -
Uncovering the power of synergy: a hybrid human–machine model for maximizing AI properties and human expertise
Citation: Critical Care 2023 27:330 -
Haloperidol for the treatment of delirium in critically ill patients: an updated systematic review with meta-analysis and trial sequential analysis
Haloperidol is frequently used in critically ill patients with delirium, but evidence for its effects has been sparse and inconclusive. By including recent trials, we updated a systematic review assessing effe...
Citation: Critical Care 2023 27:329 -
Neuropsychological outcome after cardiac arrest: results from a sub-study of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial
Cognitive impairment is common following out-of-hospital cardiac arrest (OHCA), but the nature of the impairment is poorly understood. Our objective was to describe cognitive impairment in OHCA survivors, with...
Citation: Critical Care 2023 27:328 -
Authors’ reply to the comment from Uchida et al.
Citation: Critical Care 2023 27:327 -
Comment on: Results from 237 extracorporeal membrane oxygenation runs with drowned patients
Citation: Critical Care 2023 27:326 -
Estimation of transpulmonary driving pressure during synchronized mechanical ventilation using a single lower assist maneuver (LAM) in rabbits: a comparison to measurements made with an esophageal balloon
Mechanical ventilation is applied to unload the respiratory muscles, but knowledge about transpulmonary driving pressure (ΔPL) is important to minimize lung injury. We propose a method to estimate ΔPL during neur...
Citation: Critical Care 2023 27:325 -
Comment on “The Vasopressin Loading for Refractory septic shock (VALOR) study: a prospective observational study”
Citation: Critical Care 2023 27:324 -
Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG
Pneumocystis jirovecii pneumonia (PJP) is an opportunistic, life-threatening disease commonly affecting immunocompromised patients. The distribution of predisposing diseases or conditions in critically ill patien...
Citation: Critical Care 2023 27:323 -
Evidence for a personalized early start of norepinephrine in septic shock
During septic shock, vasopressor infusion is usually started only after having corrected the hypovolaemic component of circulatory failure, even in the most severe patients. However, earlier administration of ...
Citation: Critical Care 2023 27:322 -
The interaction of thrombocytopenia, hemorrhage, and platelet transfusion in venoarterial extracorporeal membrane oxygenation: a multicenter observational study
Thrombocytopenia, hemorrhage and platelet transfusion are common in patients supported with venoarterial extracorporeal membrane oxygenation (VA ECMO). However, current literature is limited to small single-ce...
Citation: Critical Care 2023 27:321 -
Performance of the ROX index in predicting high flow nasal cannula failure in COVID-19 patients: a systematic review and meta-analysis
COVID-19 patients with acute hypoxemic respiratory failure (AHRF) benefit from high flow nasal cannula (HFNC) oxygen therapy. However, delays in initiating invasive ventilation after HFNC failure are associate...
Citation: Critical Care 2023 27:320 -
Hemodynamic impact of chest compression location during cardiopulmonary resuscitation guided by transesophageal echocardiography
Citation: Critical Care 2023 27:319 -
Performance of urinary C–C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis
Urinary C–C motif chemokine ligand 14 (CCL14) has been described as an effective marker for delayed recovery of acute kidney injury (AKI), yet its efficacy has been found to vary between different trials. The ...
Citation: Critical Care 2023 27:318 -
Nasogastric tube insertion length measurement and tip verification in adults: a narrative review
Nasogastric feeding tube insertion is a common but invasive procedure most often blindly placed by nurses in acute and chronic care settings. Although usually not harmful, serious and fatal complications with ...
Citation: Critical Care 2023 27:317 -
Differential effect on mortality of the timing of initiation of renal replacement therapy according to the criteria used to diagnose acute kidney injury: an IDEAL-ICU substudy
This substudy of the randomized IDEAL-ICU trial assessed whether the timing of renal replacement therapy (RRT) initiation has a differential effect on 90-day mortality, according to the criteria used to diagno...
Citation: Critical Care 2023 27:316 -
Physiological effects of awake prone position in acute hypoxemic respiratory failure
The effects of awake prone position on the breathing pattern of hypoxemic patients need to be better understood. We conducted a crossover trial to assess the physiological effects of awake prone position in pa...
Citation: Critical Care 2023 27:315
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- ISSN: 1364-8535 (electronic)