Articles
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Citation: Critical Care 2023 27:444
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Return to work after hospitalization for sepsis: a nationwide, registry-based cohort study
Sepsis survivors commonly experience functional impairment, which may limit return to work. We investigated return to work (RTW) of patients hospitalized with sepsis and the associations with patient and clini...
Citation: Critical Care 2023 27:443 -
In-hospital extracorporeal cardiopulmonary resuscitation for patients with out-of-hospital cardiac arrest: an analysis by time-dependent propensity score matching using a nationwide database in Japan
Extracorporeal cardiopulmonary resuscitation (ECPR) has been proposed as a rescue therapy for patients with refractory cardiac arrest. This study aimed to evaluate the association between ECPR and clinical out...
Citation: Critical Care 2023 27:442 -
From pressure to tension: a model of damaging inflation stress
Although the stretch that generates ventilator-induced lung injury (VILI) occurs within the peripheral tissue that encloses the alveolar space, airway pressures and volumes monitor the gas within the interior cor...
Citation: Critical Care 2023 27:441 -
Functional recovery in a cohort of ECMO and non-ECMO acute respiratory distress syndrome survivors
The mortality benefit of VV-ECMO in ARDS has been extensively studied, but the impact on long-term functional outcomes of survivors is poorly defined. We aimed to assess the association between ECMO and functi...
Citation: Critical Care 2023 27:440 -
Critical Illness Weakness, Polyneuropathy and Myopathy: Diagnosis, treatment, and long-term outcomes
Severe weakness associated with critical illness (CIW) is common. This narrative review summarizes the latest scientific insights and proposes a guide for clinicians to optimize the diagnosis and management of...
Citation: Critical Care 2023 27:439 -
Care pathways of sepsis survivors: sequelae, mortality and use of healthcare services in France, 2015–2018
Individuals who survive sepsis are at high risk of chronic sequelae, resulting in significant health-economic costs. Several studies have focused on aspects of healthcare pathways of sepsis survivors but compr...
Citation: Critical Care 2023 27:438 -
Application of CO2 clearance to estimate cardiac output in patients with venoarterial extracorporeal membrane oxygenation
Citation: Critical Care 2023 27:437 -
The immunomodulating activity of trimodulin (polyvalent IgM, IgA, IgG solution): a post hoc analysis of the phase II CIGMA trial
The phase II CIGMA trial performed in 160 patients with severe community-acquired pneumonia (sCAP) found treatment with trimodulin (human polyvalent immunoglobulin [Ig]: ~ 23% IgM, ~ 21% IgA, ~ 56% IgG) was as...
Citation: Critical Care 2023 27:436 -
Moving toward a contemporary classification of drug-induced kidney disease
Drug-induced kidney disease (DIKD) accounts for about one-fourth of all cases of acute kidney injury (AKI) in hospitalized patients, especially in critically ill setting. There is no standard definition or cla...
Citation: Critical Care 2023 27:435 -
Dynamic change of PaO2 may affect the association between hyperoxemia and prognosis
Citation: Critical Care 2023 27:434 -
Epidemiology of ischemic stroke and hemorrhagic stroke in venoarterial extracorporeal membrane oxygenation
While venoarterial extracorporeal membrane oxygenation (V-A ECMO) provides lifesaving support for cardiopulmonary failure, complications may increase mortality, with few studies focusing on ischemic/hemorrhagi...
Citation: Critical Care 2023 27:433 -
Bayesian methods: a potential path forward for sepsis trials
Given the success of recent platform trials for COVID-19, Bayesian statistical methods have become an option for complex, heterogenous syndromes like sepsis. However, study design will require careful consider...
Citation: Critical Care 2023 27:432 -
Reliability of pulse pressure and stroke volume variation in assessing fluid responsiveness in the operating room: a metanalysis and a metaregression
Pulse pressure and stroke volume variation (PPV and SVV) have been widely used in surgical patients as predictors of fluid challenge (FC) response. Several factors may affect the reliability of these indices i...
Citation: Critical Care 2023 27:431 -
Instruments to assess post-intensive care syndrome assessment: a scoping review and modified Delphi method study
The assessment of post-intensive care syndrome (PICS) is challenging due to the numerous types of instruments. We herein attempted to identify and propose recommendations for instruments to assess PICS in inte...
Citation: Critical Care 2023 27:430 -
Effect on capillary refill time of volume expansion and increase of the norepinephrine dose in patients with septic shock
Capillary refill time (CRT) has been suggested as a variable to follow during the course of septic shock. We systematically investigated the effects on CRT of volume expansion and norepinephrine.
Citation: Critical Care 2023 27:429 -
Inflammation and altered metabolism impede efficacy of functional electrical stimulation in critically ill patients
Critically ill patients suffer from acute muscle wasting, which is associated with significant physical functional impairment. We describe data from nested muscle biopsy studies from two trials of functional e...
Citation: Critical Care 2023 27:428 -
Clinical outcomes during and beyond different COVID-19 critical illness variant periods compared with other lower respiratory tract infections
It is yet to be better understood how outcomes during and after the critical illness potentially differ between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants from other lower respirator...
Citation: Critical Care 2023 27:427 -
Fluid balance control in critically ill patients: results from as-treated analyses of POINCARE-2 randomized trial
Intention-to-treat analyses of POINCARE-2 trial led to inconclusive results regarding the effect of a conservative fluid balance strategy on mortality in critically ill patients. The present as-treated analysi...
Citation: Critical Care 2023 27:426 -
Natural language processing diagnosed behavioural disturbance phenotypes in the intensive care unit: characteristics, prevalence, trajectory, treatment, and outcomes
Natural language processing (NLP) may help evaluate the characteristics, prevalence, trajectory, treatment, and outcomes of behavioural disturbance phenotypes in critically ill patients.
Citation: Critical Care 2023 27:425 -
Diagnostic, prognostic and clinical value of left ventricular radial strain to identify paradoxical septal motion in ventilated patients with the acute respiratory distress syndrome: an observational prospective multicenter study
Acute cor pulmonale (ACP) is prognostic in patients with acute respiratory distress syndrome (ARDS). Identification of paradoxical septal motion (PSM) using two-dimensional echocardiography is highly subjectiv...
Citation: Critical Care 2023 27:424 -
A reply to analysis of static parameters in retrospective studies: limitations and interpretation
Citation: Critical Care 2023 27:423 -
Prothrombin complex concentrate (PCC) for treatment of trauma-induced coagulopathy: systematic review and meta-analyses
Trauma-induced coagulopathy (TIC) is common in trauma patients with major hemorrhage. Prothrombin complex concentrate (PCC) is used as a potential treatment for the correction of TIC, but the efficacy, timing,...
Citation: Critical Care 2023 27:422 -
Reply to Supady et al. Comment on: Extracorporeal hemoadsorption in critically ill COVID-19 patients on VV ECMO: the CytoSorb therapy in COVID-19 (CTC) registry
Citation: Critical Care 2023 27:421 -
Correction: Plasma protein biomarkers reflective of the host response in patients developing Intensive Care Unit-acquired pneumonia
Citation: Critical Care 2023 27:420 -
Subphenotypes in patients with acute respiratory distress syndrome treated with high-flow oxygen
Acute respiratory distress syndrome (ARDS) subphenotypes differ in outcomes and treatment responses. Subphenotypes in high-flow nasal oxygen (HFNO)-treated ARDS patients have not been investigated.
Citation: Critical Care 2023 27:419 -
Cefoxitin versus carbapenems as definitive treatment for extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteremia in intensive care unit: a propensity-matched retrospective analysis
Despite cefoxitin's in vitro resistance to hydrolysis by extended-spectrum beta-lactamases (ESBL), treatment of ESBL-producing Klebsiella pneumoniae (KP) infections with cefoxitin remains controversial. The aim o...
Citation: Critical Care 2023 27:418 -
Human cytomegalovirus seropositivity is associated with reduced patient survival during sepsis
Sepsis is one of the leading causes of death. Treatment attempts targeting the immune response regularly fail in clinical trials. As HCMV latency can modulate the immune response and changes the immune cell co...
Citation: Critical Care 2023 27:417 -
Redefining ARDS: a paradigm shift
Although the defining elements of “acute respiratory distress syndrome” (ARDS) have been known for over a century, the syndrome was first described in 1967. Since then, despite several revisions of its concept...
Citation: Critical Care 2023 27:416 -
How we approach titrating PEEP in patients with acute hypoxemic failure
Citation: Critical Care 2023 27:415 -
Utilization of spontaneous breathing trial, objective cough test, and diaphragmatic ultrasound results to predict extubation success: COBRE-US trial
The results of clinical and weaning readiness tests and the spontaneous breathing trial (SBT) are used to predict the success of the weaning process and extubation.
Citation: Critical Care 2023 27:414 -
Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial
The role of haloperidol as treatment for ICU delirium and related symptoms remains controversial despite two recent large controlled trials evaluating its efficacy and safety. We sought to determine whether ha...
Citation: Critical Care 2023 27:413 -
Characteristics of pulmonary artery catheter use in multicenter ICUs in Japan and the association with mortality: a multicenter cohort study using the Japanese Intensive care PAtient Database
It has been 50 years since the pulmonary artery catheter was introduced, but the actual use of pulmonary artery catheters in recent years is unknown. Some randomized controlled trials have reported no causalit...
Citation: Critical Care 2023 27:412 -
Correction to: Efficacy and safety of adjunctive corticosteroids in the treatment of severe community‑acquired pneumonia: a systematic review and meta‑analysis of randomized controlled trials
Citation: Critical Care 2023 27:411 -
Serial assessments of cardiac output and mixed venous oxygen saturation in comatose patients after out-of-hospital cardiac arrest
To assess the association with outcomes of cardiac index (CI) and mixed venous oxygen saturation (SvO2) in comatose patients resuscitated from out-of-hospital cardiac arrest (OHCA).
Citation: Critical Care 2023 27:410 -
ECMO in resuscitated drowning patients: a propensity score matched sub-analysis—a response to Jouffroy et al.
Citation: Critical Care 2023 27:409 -
How I manage differential gas exchange in peripheral venoarterial extracorporeal membrane oxygenation
Dual circulation is a common but underrecognized physiological occurrence associated with peripheral venoarterial extracorporeal membrane oxygenation (ECMO). Competitive flow will develop between blood ejected...
Citation: Critical Care 2023 27:408 -
Quantitative analysis of early apparent diffusion coefficient values from MRIs for predicting neurological prognosis in survivors of out-of-hospital cardiac arrest: an observational study
This study aimed to quantitatively analyse ultra-early brain diffusion-weighted magnetic resonance imaging (DW-MRI) findings to determine the apparent diffusion coefficient (ADC) threshold associated with neur...
Citation: Critical Care 2023 27:407 -
Interpretable machine learning models for predicting venous thromboembolism in the intensive care unit: an analysis based on data from 207 centers
Venous thromboembolism (VTE) is a severe complication in critically ill patients, often resulting in death and long-term disability and is one of the major contributors to the global burden of disease. This st...
Citation: Critical Care 2023 27:406 -
Association between early enteral nutrition and mortality in critically ill patients
Citation: Critical Care 2023 27:405 -
Analysis of static parameters in retrospective studies: limitations and interpretation
Citation: Critical Care 2023 27:404 -
Prevalence and predictors of shared decision-making in goals-of-care clinician-family meetings for critically ill neurologic patients: a multi-center mixed-methods study
Shared decision-making is a joint process where patients, or their surrogates, and clinicians make health choices based on evidence and preferences. We aimed to determine the extent and predictors of shared de...
Citation: Critical Care 2023 27:403 -
Creating the ICU of the future: patient-centred design to optimise recovery
Intensive Care survival continues to improve, and the number of ICU services is increasing globally. However, there is a growing awareness of the detrimental impact of the ICU environment on patients, families...
Citation: Critical Care 2023 27:402 -
Lower versus higher oxygen targets for out-of-hospital cardiac arrest: a systematic review and meta-analysis
Supplemental oxygen is commonly administered to patients after out-of-hospital cardiac arrest. However, the findings from studies on oxygen targeting for out-of-hospital cardiac arrest are inconclusive. Thus, ...
Citation: Critical Care 2023 27:401 -
The role of endotoxin in septic shock
Septic shock can be caused by a variety of mechanisms including direct effects of bacterial toxins such as endotoxin. Annually, approximately 5–7 million patients worldwide develop sepsis with very high endoto...
Citation: Critical Care 2023 27:400 -
The impact of higher protein dosing on outcomes in critically ill patients with acute kidney injury: a post hoc analysis of the EFFORT protein trial
Based on low-quality evidence, current nutrition guidelines recommend the delivery of high-dose protein in critically ill patients. The EFFORT Protein trial showed that higher protein dose is not associated wi...
Citation: Critical Care 2023 27:399 -
Physiological effects of lung-protective ventilation in patients with lung fibrosis and usual interstitial pneumonia pattern versus primary ARDS: a matched-control study
Although patients with interstitial pneumonia pattern (ILD-UIP) and acute exacerbation (AE) leading to severe acute respiratory failure may require invasive mechanical ventilation (MV), physiological data on l...
Citation: Critical Care 2023 27:398 -
What applications for plasma endocan measurement in intensive care? A clarification
Citation: Critical Care 2023 27:397 -
Multimodal neuromonitoring in traumatic brain injury patients: the search for the Holy Graal
Citation: Critical Care 2023 27:396 -
The association between time definition of reintubation and patient outcomes in critically ill patients: several topics should be noticed
Citation: Critical Care 2023 27:395
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- ISSN: 1364-8535 (electronic)