ADC - R (thresholds)a | AUC (95% CI) | Cut-off value | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | P─valueb |
---|---|---|---|---|---|---|---|
ADC–R(600) | 0.909 (0.863–0.943) | > 13.2 | 76.1 (68.1–82.9) | 100.0 (95.8–100.0) | 100 | 72.3 (65.9–77.8) | Reference |
ADC–R(250) | 0.813 (0.756–0.862) | > 0.4 | 45.7 (37.2–54.3) | 100.0 (95.8–100.0) | 100 | 53.4 (45.4–61.3) | < 0.001 |
ADC–R(300) | 0.843 (0.789–0.888) | > 0.9 | 55.1 (46.4–63.5) | 100.0 (95.8–100.0) | 100 | 58.1 (49.7–66.2) | 0.001 |
ADC–R(350) | 0.870 (0.819–0.911) | > 1.6 | 65.2 (56.6–73.1) | 100.0 (95.8–100.0) | 100 | 64.2 (55.4–72.3) | 0.003 |
ADC–R(400) | 0.887 (0.838–0.925) | > 2.4 | 70.3 (61.9–77.8) | 100.0 (95.8–100.0) | 100 | 67.7 (58.8–75.7) | 0.04 |
ADC–R(450) | 0.894 (0.846–0.931) | > 3.6 | 73.9 (65.8–81.0) | 100.0 (95.8–100.0) | 100 | 70.5 (61.6–78.4) | 0.07 |
ADC–R(500) | 0.901 (0.854–0.937) | > 5.2 | 75.4 (67.3–82.3) | 100.0 (95.8–100.0) | 100 | 71.7 (62.7–79.5) | 0.16 |
ADC–R(550) | 0.907 (0.861–0.942) | > 7.9 | 76.1 (68.1–82.9) | 100.0 (95.8–100.0) | 100 | 72.3 (65.9–77.8) | 0.56 |
ADC–R(650) | 0.902 (0.855–0.937) | > 20.5 | 76.8 (68.9–83.6) | 100.0 (95.8–100.0) | 100 | 72.9 (66.5–78.5) | 0.09 |
ADC–R(700) | 0.890 (0.841–0.928) | > 39.6 | 69.6 (61.2–77.1) | 100.0 (95.8–100.0) | 100 | 67.2 (58.3–75.2) | 0.02 |
ADC–R(750) | 0.873 (0.822–0.913) | > 58.2 | 64.5 (55.9–72.4) | 100.0 (95.8–100.0) | 100 | 63.7 (55.0–71.8) | 0.007 |
ADC–R(800) | 0.857 (0.804–0.900) | > 71.1 | 63.8 (55.2–71.8) | 100.0 (95.8–100.0) | 100 | 63.2 (54.5–71.3) | 0.002 |
ADC–R(850) | 0.848 (0.794–0.892) | > 79.7 | 61.6 (52.9–69.7) | 100.0 (95.8–100.0) | 100 | 61.9 (53.3–70.0) | 0.002 |
ADC–R(900) | 0.842 (0.788–0.887) | > 85.4 | 60.9 (52.2–69.1) | 100.0 (95.8–100.0) | 100 | 61.4 (52.8–69.5) | 0.002 |
ADC–R(950) | 0.843 (0.788–0.888) | > 89.4 | 63.8 (55.2–71.8) | 100.0 (95.8–100.0) | 100 | 63.2 (54.5–71.3) | 0.003 |
ADC–R(1000) | 0.842 (0.787–0.887) | > 92.3 | 63.0 (54.4–71.1) | 100.0 (95.8–100.0) | 100 | 62.8 (54.1–70.9) | 0.004 |
ADC–R(1050) | 0.841 (0.787–0.887) | > 94.7 | 63.0 (54.4–71.1) | 100.0 (95.8–100.0) | 100 | 62.8 (54.1–70.9) | 0.004 |
ADC–R(1100) | 0.842 (0.788–0.887) | > 96.8 | 63.0 (54.4–71.1) | 100.0 (95.8–100.0) | 100 | 62.8 (54.1–70.9) | 0.005 |
ADC–R(1150) | 0.842 (0.787–0.887) | > 98.5 | 62.3 (53.7–70.4) | 100.0 (95.8–100.0) | 100 | 62.3 (53.7–70.4) | 0.006 |