Table 1 Baseline characteristics
From: Dyssynchronous diaphragm contractions impair diaphragm function in mechanically ventilated patients
Characteristic | Distribution (mean (SD)) (n = 45) |
|---|---|
Age (years) | 60 (14) |
Sex (female) | 24 (53%) |
Height (cm) | 166 (9) |
Weight (kg) | 79 (27) |
Admitting diagnosis | |
 Pneumonia | 22 (49%) |
 Acute respiratory distress syndrome | 10 (22%) |
 Non-pulmonary sepsis | 7 (16%) |
 Acute brain injury | 6 (13%) |
  Intracerebral hemorrhage | 3 (7%) |
  Subarachnoid hemorrhage | 1 (2%) |
  Ischemic stroke | 1 (2%) |
  Traumatic brain injury | 1 (2%) |
Comorbidities | |
 Asthma | 3 (7%) |
 Chronic obstructive pulmonary disease | 5 (11%) |
 Interstitial lung disease | 3 (7%) |
 Obstructive sleep apnea | 5 (11%) |
 Congestive heart failure | 4 (9%) |
 Cirrhosis | 2 (4%) |
 Chronic kidney disease | 5 (11%) |
 End-stage renal disease on dialysis | 4/43 (9%) |
 Diabetes | 8 (22%) |
 Stroke | 2 (4%) |
 Immunocompromise | 5 (10%) |
SAPS II score (median, interquartile range) | 47 (42–63) |
On veno-venous extracorporeal life support | 9 (20%) |
PaO2/FiO2 (mm Hg) (median, IQR) | 149 (110–170) |
Glasgow Coma Scale (median, IQR) | 9 (3–15) |
Ventilator settings at enrolment | |
 Mode | |
  ACVC | 5 (11%) |
  ACPC | 33 (73%) |
  PSV | 7 (16%) |
 Peak pressure (cm H2O) (median, IQR) | 25 (20–29) |
 PEEP (cm H2O) (median, IQR) | 10 (5–12) |
 Inspiratory pressure (median, IQR) | 10 (10–18) |
 Tidal volume (mL/kg PBW) | 6.2 (2.5) |
 Minute volume (L/min) (median, IQR) | 8.3 (6.2–11.0) |
 FiO2 (median, IQR) | 0.60 (0.50–0.80) |