Table 2 Hemodynamic parameters before (H0) and 1 h (H1) after fluid infusion
Saline (n = 21) | Albumin (n = 29) | P value At H1 | |||||
|---|---|---|---|---|---|---|---|
H0 | H1 | P value *H0–H1 | H0 | H1 | P value* H0–H1 | P value Sal vs Alb # | |
HR, bpm | 91 [77–115] | 95 [71–122] | 0.50 | 101 [85–115] | 100 [82–116] | 0.14 | 0.65 |
MAP, mmHg | 75 [67–78] | 74 [68–79] | > 0.99 | 72 [69–81] | 76 [70–84] | 0.27 | 0.33 |
Norepinephrine, n(%) | 13 (62) | 13 (62) | > 0.99 | 20 (69) | (68) | > 0.99 | > 0.99 |
Dose, µg/kg/min | 0.39 [0.3–0.48] | 0.30 [0.29–0.4] | 0.08 | 0.70 [0.3–1] | 0.63 [0.3–0.9] | 0.25 | 0.03 |
Cardiac index, L/min/m2 | 2.4 [2.2–2.9] | 2.5 [2–2.8] | 0.65 | 2.3 [1.9–2.8] | 2.5 [2–2.9] | 0.15 | 0.90 |
CRT (sec) | 3.5 [3.2–3.9] | 3.1 [2.6–3.4] | < .001 | 3.6 [3.4–4.0] | 2.7 [2.1–3.2] | < .001 | 0.13 |
Mottling score | 2 [1–3] | 1 [1–3] | 0.50 | 1 [1–3] | 1 [0–2] | < .001 | 0.18 |