Fig. 4From: Proenkephalin as a biomarker correlates with acute kidney injury: a systematic review with meta-analysis and trial sequential analysisUnivariable meta-regression and subgroup analysis for sensitivity and specificity of PENK for the early detection of AKI. AKI, Acute kidney injury; PENK, proenkephalin A 119-159; HTN, hypertension; DM, diabetes mellitus; CHF, congestive heart failure; CI, confidence interval; CRS, cardiorenal syndrome; KDIGO, Kidney Disease: Improving Global OutcomesBack to article page