| Gradual VAP (n = 42) | IVAC (n = 34) | P value |
---|---|---|---|
At the time of VAP diagnosis | |||
 MV duration before VAP, days | 9.32 ± 2.35 | 9.02 ± 3.51 | 0.658 |
 Early VAP | 6 (14.29) | 0 (0) | 0.030 |
 SOFA score | 7.32 ± 2.31 | 8.01 ± 3.19 | 0.278 |
 mCPIS score | 7.19 ± 1.92 | 7.33 ± 2.03 | 0.759 |
 PaO2/FiO2, mmHg | 160.32 ± 25.17 | 151.12 ± 19.19 | 0.083 |
 Temperature, °C | 38.19 ± 1.08 | 38.23 ± 0.92 | 0.864 |
 WBC, ×109/L | 13.42 ± 3.28 | 12.12 ± 3.06 | 0.096 |
Outcome | |||
 Empiric treatment failure (72 h) | 5 (11.90) | 11 (32.35) | 0.046 |
 ICU stay, days | 18.32 ± 5.19 | 20.78 ± 4.73 | 0.029 |
 Hospital stay, days | 28.17 ± 6.32 | 31.92 ± 8.14 | 0.036 |
 Days of MV | 15.23 ± 5.42 | 18.39 ± 7.14 | 0.031 |
 Total antibiotics expenditures,USD | 4058.34 ± 273.56 | 5425.89 ± 385.74 | <0.001 |