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Table 2 Nutritional intake

From: A randomized controlled pilot study to evaluate the effect of an enteral formulation designed to improve gastrointestinal tolerance in the critically ill patient—the SPIRIT trial

 

Peptamen® AF (n = 46)

Isosource® Energy (n = 44)

Treatment effect

p value

 

n

Median (IQR)

n

Median (IQR)

Median differencea (95% CI)

 

Calorie intake, Kcal/kg/day

41

18.0 (12.5–20.9)

38

19.7 (17.3–23.1)

−2.6 (−5.3 to 0.2)

0.08

Protein intake, g/kg/day

41

1.13 (0.78–1.31)

38

0.80 (0.70–0.94)

0.27 (0.12–0.43)

<0.001

Accumulated caloric deficit during EN/day, Kcal

45

−410 (−984 to −115)

43

−171 (−455 to −4)

−222 (−438 to −45)

0.014

 

n

Median (95% CI)

n

Median (95% CI)

HR (95% CI)

 

Length of EN, days

46

5.0 (3.6– to 6.4)

44

7.0 (5.3– to 8.7)

1.35 (0.80–2.26)

0.26

Time to reach the full caloric goal, days

46

2.2 (0.8– to 3.7)

44

2.0 (1.3– to 2.7)

0.70 (0.42–1.16)

0.16

 

n

No. of events (pd)

n

No. of events (pd)

Rate ratio (95% CI)

 

Days with parenteral nutrition supplementation

46

5 (253 pd)

44

2 (287 pd)

2.84 (0.28–28.61)

0.38

  1. a Hodges–Lehmann median differences
  2. CI confidence interval, EN enteral nutrition, HR hazard ratio, IQR interquartile range, pd person days