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Table 4 Further analysis on mortality

From: Use of noninvasive ventilation in immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis

 

Studies number

Patient number

Event in NIV group

Event in control group

Risk ratio (95% CI)

I 2

P

Short-term mortality

4

506

82 of 257 (31.9%)

110 of 249 (44.2%)

0.73 (0.58, 0.91)

64%

0.04

ICU mortality

3

466

54 of 237 (22.8%)

73 of 229 (31.9%)

0.72 (0.53, 0.97)

33%

0.03

Hospital mortality

4

506

82 of 257 (31.9%)

110 of 249 (44.2%)

0.73 (0.58, 0.91)

64%

0.04

Patients with PaO2/FiO2 < 200

3

541

92 of 228 (40.4%)

114 of 227 (50.2%)

0.77 (0.61, 0.98)

13%

0.03

Patients with PaO2/FiO2 > 200

2

126

29 of 62 (46.8%)

45 of 64 (70.3%)

0.46 (0.09, 2.34)

88%

0.35

Patients with diagnosis of cancer and transplantation

5

507

85 of 258 (32.9%)

113 of 249 (45.4%)

0.68 (0.48, 0.97)

58%

0.03

Patients with diagnosis of drug-related immunosuppression

2

81

7 of 33 (21.2%)

5 of 30 (16.7%)

0.95 (0.48, 1.87)

0%

0.37

  1. ICU intensive care unit, NIV noninvasive ventilation, PaO 2 /FiO 2 ratio of arterial pressure of oxygen/fraction of inspired oxygen