Table 1 Characteristics of the study population
Characteristics | Data |
|---|---|
Demographic characteristics | |
Age, days | 95.8 ± 91.1 |
≤ 28 days of birth | 75 (37.5) |
≤ 48 h of birth | 5 (2.5) |
Weight, kg | 4.4 ± 1.5 |
Medical history before surgery | |
Genetic syndrome | 8 (4) |
Resternotomy | 18 (9) |
Cardiopulmonary resuscitation | 2 (1) |
Mechanical ventilation | 11 (5.5) |
Inotropic support | 3 (1.5) |
Infection | 19 (9.5) |
Enteropathy | 4 (2) |
Medication before surgery | |
Furosemide | 42 (21) |
Spironolactone | 12 (6) |
Angiotensin-converting enzyme inhibitors | 28 (14) |
Beta blockers | 12 (6) |
Prostaglandin E1 | 44 (22) |
Aminoglycoside antibiotics | 31 (15.5) |
Vancomycin | 18 (9) |
Angiography within 1 week before surgery | 22 (11) |
Intra-operative variables | |
STS-EACTS Congenital Heart Surgery Mortality Score | 0.94 ± 0.79 |
Duration of cardiopulmonary bypass, minutes | 118.2 ± 63.0 |
Surgery requiring aortic cross-clamping | 190 (95) |
Duration of aortic cross-clamping, minutes | 62.9 ± 33.9 |
Ultrafiltration rate, ml kg−1 min−1 of bypass | 1.4 ± 0.6 |
Surgery requiring deep hypothermic circulatory arrest | 18 (9) |
Packed red blood cell transfusions, ml | 469.9 ± 153.9 |
Fresh frozen plasma transfusions, ml | 221.1 ± 116.4 |
Platelet transfusions, ml | 61.8 ± 32.7 |
Post-operative variables | |
Requirement for delayed sternal closure | 38 (19) |
Requirement for extracorporeal membrane oxygenation | 3 (1.5) |
Peak lactacidemia within 6 h of surgery, mmol L−1 | 3.8 ± 2.0 |
Peak lactacidemia within 48 h of surgery, mmol L−1 | 3.7 ± 1.9 |
Vasoactive-inotropic score within 48 h of surgery, μg kg−1 min−1 | 15.05 ± 7.29 |
Delay to sternal closure, days | 3.9 ± 3.5 |
Post-operative renal variables | |
Peak serum creatinine within 48 h of surgery, mmol L−1) | 49.2 ± 23.1 |
Peak ΔsCr within 48 h of surgery, % | 26.4 ± 47.1 |
Mean urine output within 24 h of surgery, ml kg−1 h−1 | 4.1 ± 2.7 |
Negative fluid balance, ml kg−1 24 h−1 | −28.06 ± 26.8 |
Peritoneal dialysis | 16 (8) |
Duration of peritoneal dialysis, days | 0.24 ± 0.96 |
AKI stage according to AKIN system | |
Stage 1 | 16 (8) |
Stage 2 | 8 (4) |
Stage 3 | 17 (8.5) |
Duration of mechanical ventilation, days | 1 [0–5] |
Duration of intensive care unit stay, days | 4.5 [2–7] |
In-hospital death | 8 (4) |