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Table 2 Validity values of skin and NC culture and superficial culture (skin + hubs) for prediction of catheter colonization and C-RBSI

From: Vascular catheter colonization: surveillance based on culture of needleless connectors

CULTURE

S%

95% CI

SP%

95% CI

PPV%

95% CI

NPV%

95% CI

Validity index

95% CI

Prevalence

95% CI

LR+

95% CI

LR-

95% CI

Catheter colonization

Skin+NCs

77.8

(45.0-100)

52.9

(38.3-67.6)

22.6

(6.2-38.9)-

93.1

(82.2-100)

56.7

(43.3-70.0)

15.0

(5.1-24.9)

1.65

(1.05-2.60)

0.42

(0.12-1.46)

Skin+hubs

66.7

(30.3-100)

86.3

(75.8-92.0)

46.1

(15.2-77.1)

93.6

(85.6-100)

83.3

(73.0-93.6)

15.0

(5.1-24.9)

4.86

(2.12-11.13)

0.39

(0.15-0.98)

C-RBSI

Skin+NCs

100

(75.0-100)

50.0

(36.3-63.7)

6.4

(0.0-16.7)

100

(98.3-100)

51.7

(38.2-65.1)

3.3

(0.0-8.7)

2.00

(1.55-2.59)

NA

Skin+hubs

100

(75.00-100)

81.0

(70.0-91.9)

15.4

(0.0-38.8)

100

(98.9-100)

76.8

(67.0-86.6)

3.3

(0.0-8.7)

5.27

(3.10-8.98)

NA

  1. S, sensitivity; SP, specificity; PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR-, negative likelihood ratio; CI, confidence interval; NA, not applicable; C-RBSI, catheter-related bloodstream infection