Table 2 Histological lung injury score

From: Open lung approach associated with high-frequency oscillatory or low tidal volume mechanical ventilation improves respiratory function and minimizes lung injury in healthy and injured rats

		UI	SW	LPS
Haemorrhage	LP-CMV	0.0 (0.0/0.0)	0.0 (0.0/0.0)	2.0 (1.0/3.0)
	BP-CMV	0.0 (0.0/0.0)	1.0 (0.0/1.0)	1.0 (1.0/3.0)
	HFOV	0.0 (0.0/0.0)	1.0 (0.0/1.5)	2.0 (1.0/2.0)
Inflammation	LP-CMV	1.0 (0.0/2.0)	2.0 (2.0/3.0)	4.0 (4.0/4.0)^a,b
	BP-CMV	1.0 (0.75/1.0)	1.0 (1.0/2.0)	3.0 (3.0/4.0)
	HFOV	1.0 (0.0/1.25)	2.0 (1.0/2.0)	3.0 (3.0/4.0)
Oedema	LP-CMV	0.0 (0.0/0.0)	3.0 (2.5/4.0)^a,b	2.0 (1.0/2.0)
	BP-CMV	0.0 (0.0/0.0)	0.0 (0.0/2.0)	2.0 (0.0/2.0)
	HFOV	0.0 (0.0/0.0)	0.0 (0.0/0.0)	1.0 (0.0/2.0)
Atelectasis	LP-CMV	2.5 (1.5/3.25)^b	2.0 (1.0/2.0)	2.5 (2.0/3.75)^a
	BP-CMV	1.0 (1.0/2.0)^c	2.0 (1.0/2.5)	1.0 (0.0/2.0)
	HFOV	0.0 (0.0/1.0)	1.0 (0.5/1.5)	1.0 (1.0/2.0)
Overinflation	LP-CMV	0.0 (0.0/1.5)^a,b	2.0 (2.0/3.0)	1.0 (0.25/1.75)
	BP-CMV	2.0 (1.75/3.25)	1.0 (1.0/2.0)	2.0 (1.0/2.0)
	HFOV	2.0 (1.75/2.5)	2.0 (1.5/3.5)	3.0 (1.0/3.0)
Total lung injury score (sum)	LP-CMV	4.0 (3.75/5.0)	10.0 (9.0/11.0)^a,b	12 (10.25/13.0)^a
	BP-CMV	4.5 (3.0/6.0)	7.0 (5.5/7.5)	10.0 (8.0/10.0)
	HFOV	3.5 (2.0/5.0)	6.0 (5.0/6.0)	10.0 (9.0/11.0)

Baseline measurements; LP-CMV, controlled mechanical with low PEEP; BP-CMV, controlled mechanical ventilation with "best" PEEP; HFOV, high-frequency oscillatory ventilation. Values are medians and interquartile (25%-75%) range. ^aP < 0.05 LP-CMV vs. BP-CMV. ^bP < 0.05 LP-CMV vs. HFOV. ^cP < 0.05 BP-CMV vs. HFOV.

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