Table 6 Dosing of currently available antifungals for treating candidemia
From: Bench-to-bedside review: Therapeutic management of invasive candidiasis in the intensive care unit
Drug | Loading dose (first 24 hours) | Daily dose |
|---|---|---|
Fluconazole | 800 mg (12 mg/kg) | 400 mg (6 mg/kg) |
Itraconazole | - | 200 mg/day* |
Voriconazole | 6 mg/kg every 12 hours for first two doses | 3 mg/kg every 12 hours |
Posaconazole | - | 200 mg × 3* |
Amphotericin B deoxycholate | - | 0.5 to 1 mg/kg |
Liposomal amphotericin B | - | 3 mg/kg |
Lipid complex amphotericin B | - | 5 mg/kg |
Anidulafungin | 200 mg | 100 mg |
Caspofungin | 70 mg | 50 mg |
Micafungin | - | 100 mg |