Figure 2From: Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in miceFlagellin triggers IκBα phosphorylation and degradation in mouse organs. Phosphorylation of inhibitor of kappaB alpha (IκBα), associated with IκBα degradation, 30 minutes after flagellin (1 μg/mouse) or saline (sham) in mouse lung, liver, gut and kidney; α-tubulin and β-actin, loading controls. Densitometric analysis, * P < 0.05 flagellin vs sham, t-test (n = 5 mice/group).Back to article page