Clinical review: Intra-abdominal hypertension: does it influence the physiology of prone ventilation?

Table 3 Consideration of relevant intra-abdominal conditions in randomized trials and meta-analyses concerning prone position ventilation

Study	Pulmonary vs. extrapulmonary ARDS/ALI	IAP	BMI	Free abdominal suspension?
Randomized controlled studies of ALI/ARDS/acute respiratory failure
Gattinoni and colleagues [4]	76% DP	NR	NR	NR
Guerin and colleagues [9]	Partially reported	NR	NR	NR
Curley and colleagues [48]^a	84% DP	NR	NR	Suspended
Papazian and colleagues [13]	79% DP	NR	NR	No suspension
Voggenreiter and colleagues [49]	NR	NR	NR	NR
Mancebo and colleagues [10]	62% DP	NR	NR	NR
Chan and colleagues [14]	100% DP	NR	NR	No suspension
Demory and colleagues [51]^b	91% DP	NR	NR	No suspension
Fernandez and colleagues [11]	65% DP	NR	NR^c	NR
Taccone and colleagues [12]	>65% DP^d	NR	25.3^e	No suspension^f
Other randomized controlled studies of prone ventilation
Beuret and colleagues [50]^g	NA	NC	NC	No suspension
Meta-analyses
Alsaghir and Martin [7]	NC	NC	NC	NC
Tiruvoipati and colleagues [8]	Partially^h	NC	NC	NC
Sud and colleagues [18]	NC	NC	NC	NC
Abroug and colleagues [19]	NR	NC	NC	NC
Kopterides and colleagues [17]	NC	NC	NC	NC
Sud and colleagues [52]	NC	NC	NC	NC

ALI, acute lung injury; ARDS, acute respiratory distress syndrome; BMI, body mass index; DP, direct pulmonary; IAP, intra-abdominal pressure; NA, not applicable; NC, not considered; NR, not reported. ^aPediatric study. ^bThree arms examining combinations of conventional, prone, and high-frequency oscillatory techniques. ^cIdeal body weight only reported. ^dSixty-five percent direct pulmonary, 6.5% sepsis and trauma, 23% other. ^eMean population BMI, but not controlled for. ^fEighty percent not possible to suspend, 20% not reported. ^gEvaluated prone ventilation in setting of coma. ^hExamines reporting of the most frequent cause of respiratory failure.

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