Table 2 Characteristics of 32 patients who had confirmed influenza A (H1N1)v viral primary pneumonitis
From: Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain
Variables | Value |
|---|---|
Age, years | |
Mean (SD) | 40 (13.9) |
Median (IQR) | 36 (31 to 52) |
Male sex, n (%) | 21 (73.3) |
APACHE II score, mean (SD) | 13.8 (6.4) |
SOFA score, mean (SD) | 7.1 (3.3) |
Days from onset symptoms to ICU admission | |
Mean (SD) | 3.9 (2.2) |
Median (IQR) | 3 (2 to 6) |
Days from ICU admission to diagnosis | |
Mean (SD) | 3.3 (3.1) |
Median (IQR) | 2 (1 to 6) |
Days from onset symptoms to first antiviral dose | |
Mean (SD) | 5.7 (5.1) |
Median (IQR) | 4 (1 to 8) |
Laboratory finding, median (IQR) | |
Leukocyte count (per mm3) | 5650 (3000 to 9200) |
Platelets count (per mm3) | 152.000 (124.00 to 227.000) |
Serum lactate dehydrogenase (U/L) | 953 (728 to 1230) |
Serum creatine kinase (U/L) | 392 (226 to 3047) |
Serum creatinine (mg/dL) | 0.87 (0.63 to 1.22) |
AST (U/L) | 62 (38 to 119) |
ALT (U/L) | 51 (35 to 111) |
Mechanical ventilation on admission, n (%) | |
NO | 8 (25) |
Non-invasive | 2 (6.2) |
Invasive | 22 (68.8) |
Adverse event, n (%) | |
Vasopressor drugs | 20 (62.5) |
Hemodialysis | 2 (6.2) |
Hemofiltration | 5 (15.6) |
Refractory hypoxemia requiring prone ventilation | 8 (25.0) |
Secondary superinfection | 3 (9.3) |
Opacity in initial x-ray chest, n (%) | |
1/4 quadrants | 5 (15.6) |
2/4 quadrants | 4 (12.5) |
3/4 quadrants | 8 (25.0) |
4/4 quadrants | 15 (46.9) |