Table 2 Comparison of inflammatory marker levels and cytokeratin measurements in the volunteer, postoperative, and septic groups at baseline
Healthy (n = 18) | Postoperative (n = 28) | Sepsis (n = 101) | |
|---|---|---|---|
IL-6 (pg/ml) | 0.0; 0.0 to 0.8 | 216.7; 48.8 to 360.5 | 160.5; 58.8 to 448.8 |
P values | Healthy vs. Postoperative: P < 0.001*** | ||
Healthy vs. Sepsis: P < 0.001*** | |||
Postoperative vs. Sepsis: P = 0.604 | |||
sICAM-1 (ng/ml) | 219.6; 195.2 to 285.1 | 213.7; 192.3 to 293.8 | 444.7; 330.3 to 665.5 |
P value | Healthy vs. Postoperative: P = 0.819 | ||
Healthy vs. Sepsis: P < 0.001*** | |||
Postoperative vs. Sepsis: P < 0.001*** | |||
sVCAM-1 (ng/ml) | 1524.7; 991.2 to 2038.0 | 1268.0; 1167.7 to 1550.8 | 1147.9; 883.5 to 2047.4 |
P value | Healthy vs. Postoperative: P = 0.545 | ||
Healthy vs. Sepsis: P = 0.280 | |||
Postoperative vs. Sepsis: P = 0.450 | |||
Total CK-18 (U/l) | 241.9; 216.9 to 285.3 | 558.7; 465.6 to 793.0 | 1643.8; 1096.5 to 2633.5 |
P value | Healthy vs. Postoperative: P < 0.001*** | ||
Healthy vs. Sepsis: P < 0.001*** | |||
Postoperative vs. Sepsis: P < 0.001*** | |||
CK-18 fragments (U/l) | 143.7; 134.4 to 168.1 | 116.0; 106.6 to 165.1 | 392.6; 258.4 to 654.5 |
P value | Healthy vs. Postoperative: P = 0.250 | ||
Healthy vs. Sepsis: P < 0.001*** | |||
Postoperative vs. Sepsis: P < 0.001*** | |||
Ratio | 0.58; 0.55 to 0.67 | 0.22; 0.18 to 0.25 | 0.24; 0.14 to 0.35 |
P value | Healthy vs. Postoperative: P < 0.001*** | ||
Healthy vs. Sepsis: P < 0.001*** | |||
Postoperative vs. Sepsis: P = 0.507 | |||