Table 2 Stability of time-dependent antibiotics in solution for intravenous infusion
Antibiotic | Time of stability at room temperature (+25°C; hours) | Maximum concentration tested (mg/l) | Solvent |
|---|---|---|---|
Piperacillin/tazobatam [52] | >72 | 128,000 | Sterile water for injection |
Ceftazidime [52] | 24 | 120,000 | Sterile water for injection |
Cefepime [52] | 13 | 50,000 | Sterile water for injection |
Imipenem [52] | 3.30 | 8,000 | Sterile water for injection |
Meropenem [52] | 5.15 | 64,000 | Sterile water for injection |
Vancomycin [53] | >696 | NA | Sterile water for injection, sodium chloride solution (0.9%; pH 5.4), dextrose solution (5%; pH 4.2) |