Table 2 Perioperative surgical and medical characteristics

Preoperative chemotherapy

10.8

14.4

0.080

Type of surgery (% cases)

   Pneumonectomy or bi-lobectomy

21.4

17.6

0.129

   Lobectomy

54.2

56.1

0.575

   Lesser resection

18.7

20.5

0.542

   Explorative thoracotomy

5.4

3.2

0.099

Pathologic stage (% patients)

   Ia and Ib

42

44

0.531

   IIa and IIb

22

23

0.750

   IIIa

18

19

0.733

   IIIb and IV

11

8

0.389

   Other

7

6

0.833

Thoracic epidural analgesia (% patients)

83.7

95.0*

< 0.001

Intraoperative period

   Duration of anesthesia (minutes)

166 (62)

176 (74)

0.228

   Duration of surgery (minutes)

114 (47)

121 (56)

0.354

   Duration of one-lung ventilation (minutes)

71 (18)

74 (20)

0.421

   Total intraoperative fluid intake (ml/kg/hour)

5.6 (2.8)

5.8 (2.9)

0.587

   Intravenous crystalloids (ml/kg/hour)

3.6 (1.4)

3.5 (1.6)

0.652

   Intravenous colloids (ml/kg/hour)

2.0 (1.5)

2.3 (1.8)

0.187

   Red blood cell transfusion (% patients)

1.50

1.61

0.991

   Urine output (ml/kg/hour)

1.8 (1.2)

1.5 (1.4)

0.287

   Phenylephrine (mg)

528 (443)

588 (487)

0.338

   Ephedrine (mg)

15 (13)

16 (14)

0.542

   Cumulative fluid intake (24 hours) (ml/kg/hour)

6.4 (3.2)

6.6 (3.1)

0.385

Postoperative period

   Total fluid intake (ml/24 hours)

1,657 (573)

1,496 (608)

0.182

   Red blood cell transfusion (% patients)

2.25

1.79

0.890

   Urine output (ml/24 hours)

868 (334)

781 (234)

0.254

   Chest drainage (ml/24 hours)

378 (172)

342 (125)

0.774

   PaO₂/FIO₂ (kPa)

45.1 (6.2)

44.7 (5.9)

0.513

   Blood hemoglobin at POD1 (g/l)

119 (13)

121 (20)

0.834

   Serum creatinine at POD1 (mg/l)

93 (30)

84 (31)

0.303