Table 3 Analyses of blood glucose (BG) levels and insulin therapy across groups with different severities of sepsis
From: The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability
BG and insulin analyses | Sepsis n = 47 | Severe sepsis n = 83 | Septic shock n = 61 | p valuesa |
|---|---|---|---|---|
Mean BG level during sepsis (mg/dl; mean/SD) | 132.0 (21.4) | 142.4 (25.7) | 140.2 (21.4) | 0.0516b |
Median BG level during sepsis (mg/dl; median/IQR) | 133.7 (113.5 to 142.1) | 142.1 (122.5 to 158.3) | 133.5 (124.0 to 161.3) | 0.0458 c |
Mean morning BG level during sepsis (mg/dl; mean/SD) | 124.4 (17.5) | 131.0 (± 32.5) | 135.1 (54.4) | 0.7227b |
Median SD during sepsis (mg/dl; median/IQR) | 29.5 (19.2 to 35.9) | 38.5 (26.0 to 52.1) | 31.1 (25.2 to 46.9) | 0.0090 c |
Median morning BG level during sepsis (mg/dl; median/IQR) | 126.3 (113.0 to 136.0) | 122.5 (107.2 to 152.0) | 121.8 (109.0 to 139.5) | 0.9552c |
Median number of BG measurements per day during sepsis (median/IQR) | 7.0 (5.6 to 8.5) | 7.0 (5.5 to 8.5) | 8.7 (7.6 to 9.7) | 0.0001 c |
Absolute number of critical hypoglycaemic episodes * | 1 | 6 | 7 | |
Rate of critical hypoglycaemia per 100 hours of IIT (median/IQR) | 0.17 (single episode) | 0.81 (0.48 to 1.01) | 0.37 (0.16 to 0.58) | 0.3278c |
Median time interval of BG measurements within 24 hour prior to the critical hypoglycaemic episode (hours; median/IQR) | 4.1 (3.6 to 5.2) | 2.0 (1.5 to 2.3) | 2.5 (1.5 to 2.8) | 0.1715c |
Median time interval from the last BG measurement before to the critical hypoglycaemic episode itself (hours; median/IQR) | 3.9 (single episode) | 1.4 (0.7 to 3.1) | 2.4 (1.3 to 4.3) | 0.5619c |